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  1. The objective of rehabilitation following meniscal repair is to promote healing by limiting stresses on repairs, while simultaneously preserving muscle strength and joint motion. Both protective protocols limi...

    Authors: Patrick C. McCulloch, Hugh L. Jones, Kendall Hamilton, Michael G. Hogen, Jonathan E. Gold and Philip C. Noble
    Citation: Journal of Experimental Orthopaedics 2016 3:11
  2. The purpose of this study was to quantify the meniscal root anatomy of the New Zealand white rabbit to better understand this animal model for future in vitro and in vivo joint degeneration studies.

    Authors: David Civitarese, Tammy L. Haut Donahue, Christopher M. LaPrade, Adriana J. Saroki, Samuel G. Moulton, Jason M. Schon and Robert F. LaPrade
    Citation: Journal of Experimental Orthopaedics 2016 3:10
  3. There has been debate on which blood components should be included in autologous therapies. Autologous Protein Solution (APS) is a unique blood-derived therapy composed of concentrated white blood cells, plate...

    Authors: William King, Walter van der Weegen, Rogier Van Drumpt, Hans Soons, Krista Toler and Jennifer Woodell-May
    Citation: Journal of Experimental Orthopaedics 2016 3:9
  4. Failure of the scapulohumeral rhythm (SHR) is observed in patients with shoulder joint dysfunction. The SHR reportedly has a 2:1 ratio during scapular upward rotation with arm elevation. However, three-dimensi...

    Authors: Kazuya Madokoro, Masafumi Gotoh, Yoshihiro Kai, Tatsuyuki Kakuma, Takashi Nagamatsu and Naoto Shiba
    Citation: Journal of Experimental Orthopaedics 2016 3:8
  5. Meniscal injuries are a risk factor for osteoarthritis (OA). While a mechanical pathway between meniscal injury and OA has been described, the biological effects of inflammation on this pathway have yet to be ...

    Authors: Takahiro Ogura, Miyako Suzuki, Yoshihiro Sakuma, Kazuyo Yamauchi, Sumihisa Orita, Masayuki Miyagi, Tetsuhiro Ishikawa, Hiroto Kamoda, Yasuhiro Oikawa, Izumi Kanisawa, Kenji Takahashi, Hiroki Sakai, Tomonori Nagamine, Hideaki Fukuda, Kazuhisa Takahashi, Seiji Ohtori…
    Citation: Journal of Experimental Orthopaedics 2016 3:7
  6. The purpose of this study was to investigate periosteal vessels location as intra-operative landmarks in distal femoral osteotomies and focused on the branching pattern of the vascular supply of the medial and...

    Authors: J. A. D. van der Woude, R. J. van Heerwaarden and R. L. A. W. Bleys
    Citation: Journal of Experimental Orthopaedics 2016 3:6
  7. With the advent of MRI (Magnetic Resonance Imaging), Synovial lesions around knee are being more and more easily detected. Synovial lesions of knee present with boggy swelling, effusion, pain, and restriction ...

    Authors: Kumar Kaushik Dash, Piyush Vishwas Gavai, Roshan Wade and Amyn Rajani
    Citation: Journal of Experimental Orthopaedics 2016 3:5
  8. The anterior cruciate ligament (ACL) plays an important role in anterior knee stability by preventing anterior translation of the tibia on the femur. Rapid translation of the tibia with respect to the femur pr...

    Authors: Jawad F. Abulhasan, Cameron M. Anley, Martyn D. Snow and Michael J. Grey
    Citation: Journal of Experimental Orthopaedics 2016 3:4
  9. Ankle osteoarthritis (AOA) is a severe pathology, mostly affecting a post-traumatic young population. Arthroscopic debridement, arthrodiastasis, osteotomy are the current joint sparing procedures, but, in the ...

    Authors: Francesco Castagnini, Camilla Pellegrini, Luca Perazzo, Francesca Vannini and Roberto Buda
    Citation: Journal of Experimental Orthopaedics 2016 3:3
  10. Much research is currently ongoing into new therapies for cartilage defect repair with new biomaterials frequently appearing which purport to have significant regenerative capacity. These biomaterials may be c...

    Authors: Conor J. Moran, Ashwanth Ramesh, Pieter A. J. Brama, John M. O’Byrne, Fergal J. O’Brien and Tanya J. Levingstone
    Citation: Journal of Experimental Orthopaedics 2016 3:1
  11. Accurate measurement of forces through the proximal radius can assess the effects of some surgical procedures on radioulnar load sharing, but is difficult to achieve given the redundant loading nature of the m...

    Authors: Nikolas K. Knowles, Michael Gladwell and Louis M. Ferreira
    Citation: Journal of Experimental Orthopaedics 2015 2:19
  12. When researchers describe data from their studies, there is no rule defining the best way to represent results. Therefore, collecting and explaining results from personal research or understanding data from pu...

    Authors: Silvia Pianigiani, Jos Vander Sloten, Walter Pascale, Luc Labey and Bernardo Innocenti
    Citation: Journal of Experimental Orthopaedics 2015 2:18
  13. The anterior cruciate ligament (ACL) injury is one of the most common in the knee. Tendons can be used as alternative grafts for ACL repair, with tendon “ligamentization” often reported in literature. The purp...

    Authors: Marco Giordano, Francesco Falciglia, Alessia Poggiaroni, Angelo Gabriele Aulisa, Pietro Savignoni and Vincenzo Guzzanti
    Citation: Journal of Experimental Orthopaedics 2015 2:17
  14. Radiofrequency ablation and percutaneous cryoneurolysis to relieve knee pain requires treating large areas to ensure coverage due to high variability in the sensory innervation of the knee and limitations of c...

    Authors: Emily Hu, Jessica Preciado, Vinod Dasa and Jason Mussell
    Citation: Journal of Experimental Orthopaedics 2015 2:16
  15. Articular cartilage has limited regeneration capacities. One of the factors that appear to affect the in vitro cultivation of articular cartilage is mechanical stimulation. So far, no combination of parameters ha...

    Authors: Jerry Natenstedt, Aimee C Kok, Jenny Dankelman and Gabrielle JM Tuijthof
    Citation: Journal of Experimental Orthopaedics 2015 2:15
  16. As several new tibial osteotomy plates recently appeared on the market, the aim of the present study was to compare mechanical static and fatigue strength of three newly designed plates with gold standard plat...

    Authors: Arnaud Diffo Kaze, Stefan Maas, Danièle Waldmann, Andreas Zilian, Klaus Dueck and Dietrich Pape
    Citation: Journal of Experimental Orthopaedics 2015 2:14
  17. A gold standard treatment for articular cartilage injuries is yet to be found, and a cost-effective and predictable large animal model is needed to bridge the gap between in vitro studies and clinical studies.

    Authors: Bjørn Borsøe Christensen, Casper Bindzus Foldager, Morten Lykke Olesen, Louise Vingtoft, Jan Hendrik Duedal Rölfing, Steffen Ringgaard and Martin Lind
    Citation: Journal of Experimental Orthopaedics 2015 2:13
  18. Calcaneal fracture malunion may evolve into arthrosis and severe foot deformities. The aim of this study was to identify differences in bony union following corrective subtalar arthrodesis with interposition o...

    Authors: Carlo Henning, Gabriel Poglia, Murilo Anderson Leie and Carlos Roberto Galia
    Citation: Journal of Experimental Orthopaedics 2015 2:10
  19. Large animal models play a crucial role in sports surgery of the knee, as they are critical for the exploration of new experimental strategies and the clinical translation of novel techniques. The purpose of t...

    Authors: Henning Madry, Mitsuo Ochi, Magali Cucchiarini, Dietrich Pape and Romain Seil
    Citation: Journal of Experimental Orthopaedics 2015 2:9
  20. Damage to the articular cartilage is an important, prevalent, and unsolved clinical issue for the orthopaedic surgeon. This review summarizes innovative basic research approaches that may improve the current u...

    Authors: Magali Cucchiarini, Christel Henrionnet, Didier Mainard, Astrid Pinzano and Henning Madry
    Citation: Journal of Experimental Orthopaedics 2015 2:8
  21. In a noticeable percentage of patients anterolateral rotational instabilities (ALRI) remain after an isolated ACL reconstruction. Those instabilities may occur due to an insufficiently directed damage of anter...

    Authors: Martin Zens, Matthias J Feucht, Johannes Ruhhammer, Anke Bernstein, Hermann O Mayr, Norbert P Südkamp, Peter Woias and Philipp Niemeyer
    Citation: Journal of Experimental Orthopaedics 2015 2:7
  22. The repetitive load to which the adolescent athlete’s body is exposed during training and competition affects bone growth. In previous studies, abnormalities of the spine and extremities of adolescent athletes...

    Authors: Páll Sigurgeir Jónasson, Lars Ekström, Hans-Arne Hansson, Mikael Sansone, Jón Karlsson, Leif Swärd and Adad Baranto
    Citation: Journal of Experimental Orthopaedics 2015 2:6
  23. Intratendinous injections may have important effects on the properties of collagen microarchitecture, morphology, and subsequent mechanical properties of the injected tendon. The purpose of this study was to e...

    Authors: John J Wilson, Kenneth S Lee, Connie Chamberlain, Ryan DeWall, Geoffrey S Baer, Marcus Greatens and Nicole Kamps
    Citation: Journal of Experimental Orthopaedics 2015 2:5
  24. Recently, healing of a ruptured anterior cruciate ligament (ACL) is reconsidered. In a previous study, we have shown that the transected ACL can heal after treatment with the triple X locking suture alone or c...

    Authors: D Tan Nguyen, Sietske Dellbrügge, Paul P Tak, Savio L-Y Woo, Leendert Blankevoort and Niek C van Dijk
    Citation: Journal of Experimental Orthopaedics 2015 2:4
  25. Patients with compartment syndromes have elevated intramuscular pressure (IMP) due to increased volume in the affected muscle. However, the accuracy of IMP as a parameter in diagnosing chronic compartment synd...

    Authors: Andreas Nilsson, Qiuxia Zhang and Jorma Styf
    Citation: Journal of Experimental Orthopaedics 2015 2:3
  26. Platelet-rich Plasma (PRP) is a fascinating biological treatment showing promising results for the management of cartilage disorders. However, despite the step forwards in this research area and the increasing...

    Authors: Francesca Vannini, Berardo Di Matteo and Giuseppe Filardo
    Citation: Journal of Experimental Orthopaedics 2015 2:2
  27. We summarize research approaches and findings on bone healing and regeneration that were presented at a workshop at the 60th annual meeting of the Orthopedic Research Society (ORS) in New Orleans in 2014. The ...

    Authors: Claudia Schlundt, Hanna Schell, Stuart B Goodman, Gordana Vunjak-Novakovic, Georg N Duda and Katharina Schmidt-Bleek
    Citation: Journal of Experimental Orthopaedics 2015 2:1
  28. The changes in synovial fluid biomarkers after intra-articular injection of hyarulonic acid (IA HA) remain controversial. We investigate the changes in the properties of synovial fluid (SF) and clinical sympto...

    Authors: Yoshihiro Kusayama, Yasushi Akamatsu, Ken Kumagai, Hideo Kobayashi, Masato Aratake and Tomoyuki Saito
    Citation: Journal of Experimental Orthopaedics 2014 1:16
  29. Inflammatory cytokines such as interleukin-1 beta (IL-1β) contribute to the progression of intervertebral disc degeneration. Previously we demonstrated, in vitro, that by delivering interleukin-1 receptor antagon...

    Authors: Deborah J Gorth, John T Martin, George R Dodge, Dawn M Elliott, Neil R Malhotra, Robert L Mauck and Lachlan J Smith
    Citation: Journal of Experimental Orthopaedics 2014 1:15
  30. There remains controversy on the role of the deltoid on glenohumeral translations during basic and pitching motions. We thus studied the passive effect of the deltoid on the deltoid glenohumeral joint center (...

    Authors: Claudio Rosso, Andreas M Mueller, Brett McKenzie, Vahid Entezari, Andrea Cereatti, Ugo Della Croce, Arun J Ramappa, Ara Nazarian and Joseph P DeAngelis
    Citation: Journal of Experimental Orthopaedics 2014 1:14
  31. The aim of this study was to investigate the effect of combining rhFGF18 or BMP-7 with a biphasic collagen/GAG osteochondral scaffold (Chondromimetic) on the repair of osteochondral defects in sheep.

    Authors: Alan Getgood, Frances Henson, Carrie Skelton, Roger Brooks, Hans Guehring, Lisa A Fortier and Neil Rushton
    Citation: Journal of Experimental Orthopaedics 2014 1:13
  32. Meniscus integrity is the key for joint health of the knee. Therefore, the main goal of every meniscus treatment should be the maintenance of as much meniscus tissue as possible.

    Authors: Peter Angele, Richard Kujat, Matthias Koch and Johannes Zellner
    Citation: Journal of Experimental Orthopaedics 2014 1:12
  33. Osteomyelitis is a devastating condition whose treatment relies on the detection of bacteria. The current standard of microbiology culture may not be adequate. Molecular biology based diagnostic procedures for...

    Authors: Brian D Mariani, Daniel S Martin, Antonia F Chen, Haruyo Yagi, Sheldon S Lin and Rocky S Tuan
    Citation: Journal of Experimental Orthopaedics 2014 1:9
  34. Several techniques have been used during the years to treat chondral and osteochondral lesions. Among them, the emerging trend in the field of osteochondral regeneration is to treat the entire osteochondral un...

    Authors: Elizaveta Kon, Giuseppe Filardo, Francesco Perdisa, Giulia Venieri and Maurilio Marcacci
    Citation: Journal of Experimental Orthopaedics 2014 1:10
  35. Trauma, osteomyelitis, bone tumour resections and congenital deformities are the main causes of bone deficiency in which autologous graft is the preferred treatment, but usually the bone supplies are limited.

    Authors: Juan Carlos Jacinto-Tinajero, Daniel Ascencio, Brenda Marquina, Jorge Barrios-Payán, Maria Concepcion Gutierrez, Miguel Gomez Lim and Rogelio Hernández Pando
    Citation: Journal of Experimental Orthopaedics 2014 1:11
  36. Aggrecan is a large proteoglycan bearing numerous chondroitin sulfate and keratan sulfate chains that endow articular cartilage with its ability to withstand compressive loads. It is present in the extracellul...

    Authors: Peter J Roughley and John S Mort
    Citation: Journal of Experimental Orthopaedics 2014 1:8
  37. The high loads on adolescent athletes’ musculoskeletal system are known to cause morphological and degenerative changes in bone, intervertebral discs and joints. It has been suggested that the cam deformity of...

    Authors: Páll Sigurgeir Jónasson, Lars Ekström, Anna Swärd, Mikael Sansone, Mattias Ahldén, Jón Karlsson and Adad Baranto
    Citation: Journal of Experimental Orthopaedics 2014 1:4
  38. Laboratory spinal biomechanical tests using human cadaveric or animal spines have limitations in terms of disease transmission, high sample variability, decay and fatigue during extended testing protocols. The...

    Authors: Tian Wang, Jonathon R Ball, Mattew H Pelletier and William R Walsh
    Citation: Journal of Experimental Orthopaedics 2014 1:3
  39. Revision anterior cruciate ligament (ACL) reconstruction requires a precise evaluation of previous tunnel locations and diameters. Enlargement of the tunnels, despite not usually affecting primary reconstructi...

    Authors: Bernardo Crespo, Cathrine Aga, Katharine J Wilson, Shannon M Pomeroy, Robert F LaPrade, Lars Engebretsen and Coen A Wijdicks
    Citation: Journal of Experimental Orthopaedics 2014 1:2
  40. Implants for fracture and/or osteotomy fixation are often tested according to basic mechanical test models such as open gap tests or 4-point-bending tests. These may be suitable to test and compare different i...

    Authors: Justus-Martijn Brinkman, Christof Hurschler, Jens Agneskirchner, Philip Lobenhoffer, René M Castelein and Ronald J van Heerwaarden
    Citation: Journal of Experimental Orthopaedics 2014 1:1