Articles

Translational applications of photopolymerizable hydrogels for cartilage repair

Articular cartilage lesions generated by trauma or osteoarthritis are the most common causes of pain and disability in patients.

Authors: Weikun Meng, Liang Gao, Jagadeesh K. Venkatesan, Guanglin Wang, Henning Madry and Magali Cucchiarini

Periosteal incarceration versus interposition adipose tissue grafting in physeal fractures: pilot study in immature rabbits

The purpose of this study is to evaluate bar formation following physeal fracture with incarcerated periosteum or adipose tissue graft using radiographic and histological methods in an immature rabbit model.

Authors: Eric W. Edmonds, Joshua D. Doan and Christine L. Farnsworth

A novel method for internal fixation of basal fifth metatarsal fracture in athletes: a cadaveric study of the F.E.R.I. technique (Fifth metatarsal, Extra-portal, Rigid, Innovative)

One of the main problems of Kirschner wire fixation of fifth metatarsal base fractures (in combination with a tension band wiring technique) seems to be hardware intolerance and several studies in athletes als...

Authors: Pieter D’Hooghe, Silvio Caravelli, Simone Massimi, James Calder, Peter Dzendrowskyj and Stefano Zaffagnini

Augmented reality-based navigation system applied to tibial bone resection in total knee arthroplasty

This pilot study was performed to examine the accuracy of the AR-KNEE system, an imageless navigation system using augmented reality (AR) technology for total knee arthroplasty. The AR-KNEE system enables the ...

Authors: Sachiyuki Tsukada, Hiroyuki Ogawa, Masahiro Nishino, Kenji Kurosaka and Naoyuki Hirasawa

Mechanical strength of a new plate compared to six previously tested opening wedge high tibial osteotomy implants

This study aimed to assess the mechanical static and fatigue strength provided by the FlexitSystem plate in medial opening wedge high tibial osteotomies (MOWHTO), and to compare it to six previously tested imp...

Authors: Arnaud Diffo Kaze, Stefan Maas, James Belsey, Alexander Hoffmann, Romain Seil, Ronald van Heerwaarden and Dietrich Pape

Biomechanical correlation at the knee joint between static lunge and single-leg drop landing - a comparative study among three different toe directions

Toe direction is a critical factor affecting knee biomechanics during various movements including closed kinetic chain (CKC) exercise and landing tasks. Physiotherapists always concentrate on the control of to...

Authors: Kengo Harato, Aiko Sakurai, Yutaro Morishige, Shu Kobayashi, Yasuo Niki and Takeo Nagura

Effects of denosumab on bone mineral density and bone turnover markers in rheumatoid arthritis patients switching from bisphosphonates

To compare the efficacy of 12-month denosumab treatment on bone mineral density (BMD) and bone turnover markers (BTMs) between treatment-naïve osteoporosis patients with rheumatoid arthritis (RA) and those wit...

Authors: Tetsuya Kaneko, Koichi Okamura, Yukio Yonemoto, Chisa Okura, Takahito Suto, Masahiro Tachibana, Hideo Sakane, Makoto Inoue and Hirotaka Chikuda

The influence of tantalum on human cell lineages important for healing in soft-tissue reattachment surgery: an in-vitro analysis

Porous tantalum is currently used in orthopaedic surgery for a variety of indications including soft tissue re-attachment. However, the clinical results have been variable and a previous laboratory study has s...

Authors: Edward C. A. Gee, Renato Eleotério, Laura M. Bowker, Adnan Saithna and John A. Hunt

An in vitro model to explore subchondral perfusion and intraosseous pressure

Little is known about subchondral perfusion physiology. We developed a 3Rs (Replace, Reduce, Refine) compliant in vitro calf foot model to explore perfusion and intraosseous pressure (IOP).

Authors: Michael Beverly and David Murray

The rebar repair for radial meniscus tears: a biomechanical comparison of a reinforced suture repair versus parallel and cross-stitch techniques

Radial meniscus tears can cause the meniscus to be completely incompetent. This serious type of meniscus tear can be difficult to repair. Techniques have been developed that juxtapose the meniscus tear edges a...

Authors: Patrick Massey, Kaylan McClary, David Parker, R. Shane Barton and Giovanni Solitro

Cluster analysis successfully identifies clinically meaningful knee valgus moment patterns: frequency of early peaks reflects sex-specific ACL injury incidence

Biomechanical studies of ACL injury risk factors frequently analyze only a fraction of the relevant data, and typically not in accordance with the injury mechanism. Extracting a peak value within a time series...

Authors: Haraldur B. Sigurðsson and Kristín Briem

Tapentadol vs oxycodone/naloxone in the management of pain after total hip arthroplasty in the fast track setting: an observational study

In recent years, joint replacement surgery has gradually progressed towards the fast-track model, and early rehabilitation immediately after surgery is regarded fundamental for optimal recovery of function: th...

Authors: Tiziana D’Amato, Federica Martorelli, Giorgia Fenocchio, Vincenzo Simili, Elizaveta Kon, Berardo Di Matteo and Marco Scardino

Characteristics of ultrasound device: a new technology for bone curettage and excavation

Ultrasonic (US) devices are used in laparoscopic, dental, and spinal surgeries, while it is difficult to use for the joint under irrigation and perfusion solutions due to lack of power. A new US device is deve...

Authors: Tatsuo Mae, Ken Nakata, Tsukasa Kumai, Yasuyuki Ishibashi, Tomoyuki Suzuki, Takamitsu Sakamoto, Tomoki Ohori, Takehito Hirose and Hideki Yoshikawa

Life is a journey

Authors: Henning Madry

Correction to: The role of intra-articular administration of Fetuin-A in post-traumatic knee osteoarthritis: an experimental study in a rat model

Following publication of the original article [1], the authors opted to correct the middle initial of co-author Despina N. Perrea from S to N. The original article has been corrected.

Authors: Eleni Pappa, Savvas Papadopoulos, Laskarina-Maria Korou, Despina N. Perrea, Spiridon Pneumaticos and Vasileios S. Nikolaou

Parametric finite element model of medial patellofemoral ligament reconstruction model development and clinical validation

Currently, there is uncertainty regarding the long-term outcome of medial patellofemoral ligament reconstructions (MPFLr). Our objectives were: (1) to develop a parametric model of the patellofemoral joint (PF...

Authors: Vicente Sanchis-Alfonso, Diego Alastruey-López, Gerad Ginovart, Erik Montesinos-Berry, Fabio García-Castro, Cristina Ramírez-Fuentes, Joan Carles Monllau, Angel Alberich-Bayarri and María Angeles Pérez

Strain behavior of native and reconstructed medial patellofemoral ligaments during dynamic knee flexion - a cadaveric study

Surgical reconstruction of the Medial Patello-Femoral Ligament (MPFL) has been recognized as an effective treatment for patients with instability despite conservative treatment. The purpose of this cadaveric s...

Authors: Mohamed Buhary Kizher Shajahan, Chaw Tat Alex Choh, Khye Soon Andy Yew, Hiok Yang Chan, Tet Sen Howe, Tjiauw Tjoen Denny Lie, Suang Bee Joyce Koh and Chee Cheng Paul Chang

Reliability of ultrasonography measurement of the anterior talofibular ligament (ATFL) length in healthy subjects (in vivo), based on examiner experience and patient positioning

The most common cause of ankle injury is the supination trauma, inflicting a partial or complete rupture of the anterior talofibular ligament (ATFL). Among conventional diagnostic tools and procedures of sport...

Authors: Karl-Heinz Kristen, Jesse Seilern und Aspang, Johannes Wiedemann, Florian Hartenbach and Hannes Platzgummer

Quadriceps muscle activity during commonly used strength training exercises shortly after total knee arthroplasty: implications for home-based exercise-selection

In the early phase after a total knee arthroplasty (TKA), patients experience multi-level weakness in the operated leg, which is caused primarily by reduced central nervous system (CNS) activation failure of t...

Authors: Thomas Linding Jakobsen, Markus Due Jakobsen, Lars Louis Andersen, Henrik Husted, Henrik Kehlet and Thomas Bandholm

A shortened uncemented stem offers comparable positioning and increased metaphyseal fill compared to a standard uncemented stem

Shortened stems are increasingly used in uncemented total hip arthroplasty (THA) as they represent a compromise between the metaphyseal anchorage of short stems and the facilitated axial alignment of standard ...

Authors: Alexandre Jacquel, Augustin Le Viguelloux, Jeremy Valluy, Mo Saffarini and Nicolas Bonin

The biomechanical role of meniscal allograft transplantation and preliminary in-vivo kinematic evaluation

Meniscus allograft transplantation (MAT) is a surgical procedure performed in patients complaining post-meniscectomy syndrome. Although the effectiveness of MAT on knee stability has been already demonstrated ...

Authors: Stefano Zaffagnini, Stefano Di Paolo, Federico Stefanelli, Giacomo Dal Fabbro, Luca Macchiarola, Gian Andrea Lucidi and Alberto Grassi

Anteversion and length of the femoral tunnel in ACL reconstruction: in-vivo comparison between rigid and flexible instrumentation

Due to it being tangential to the distal femoral axis, the anteromedial portal presents significant risk of causing iatrogenic damage, and of producing tunnels that are too short for optimal osseointegration. ...

Authors: Frank Wein, Benoit Osemont, Thomas Goetzmann, Adrien Jacquot, Jeremy Valluy, Mo Saffarini and Daniel Molé

The role of intra-articular administration of Fetuin-A in post-traumatic knee osteoarthritis: an experimental study in a rat model

The purpose of this study is to investigate the possible attenuating role of the intra-articular administration of Fetuin-A in post-traumatic secondary osteoarthritis in rats, and also its effect on the system...

Authors: Eleni Pappa, Savvas Papadopoulos, Laskarina-Maria Korou, Despina N. Perrea, Spiridon Pneumaticos and Vasileios S. Nikolaou

Optimization of leukocyte-poor platelet-rich plasma preparation: a validation study of leukocyte-poor platelet-rich plasma obtained using different preparer, storage, and activation methods

Alternative methods of platelet-rich plasma (PRP) preparation, storage, and activation that can be stably reproduced are needed to improve PRP production. The purpose of this study was to investigate the effec...

Authors: Naoya Kikuchi, Tomokazu Yoshioka, Yu Taniguchi, Hisashi Sugaya, Norihito Arai, Akihiro Kanamori and Masashi Yamazaki

The biomechanical effect of tibiofemoral conformity design for patient-specific cruciate retainging total knee arthroplasty using computational simulation

Alterations to normal knee kinematics performed during conventional total knee arthroplasty (TKA) focus on the nonanatomic articular surface. Patient-specific TKA was introduced to provide better normal knee k...

Authors: Yong-Gon Koh, Kyoung-Mi Park and Kyoung-Tak Kang

Quantitative mapping of acute and chronic PCL pathology with 3 T MRI: a prospectively enrolled patient cohort

The diagnosis of incomplete acute and chronic posterior cruciate ligament (PCL) tears can be challenging with conventional magnetic resonance (MR) imaging, particularly for injuries in which the ligament appea...

Authors: Katharine J. Wilson, Jurgen Fripp, Carly A. Lockard, Richard C. Shin, Craig Engstrom, Charles P. Ho and Robert F. LaPrade

Histological incorporation of acellular dermal matrix in the failed superior capsule reconstruction of the shoulder

Superior capsule reconstruction addresses massive rotator cuff tears using allografts and aims to restore the natural superior constraint of the shoulder and therefore shoulder biomechanics and function. There...

Authors: Matthew J. Ravenscroft, James A. Riley, Barnes W. Morgan, Dilraj S. Sandher, Saurabh S. Odak and Preethi Joseph

“Simple mechanical devices did not improve pelvis positioning in AP pelvis radiographs for reliable assessment of the acetabular orientation”

The aim of this study was to develop two simple positioning devices for anteroposterior pelvis radiographs and to evaluate their effect on accuracy of the radiographs for assessment of the acetabular orientati...

Authors: Matthias Brockmeyer, Sebastian Lott, Jonas Stroeder, Peter Fries, Stefan Wagenpfeil, Thomas Tschernig and Dieter Kohn

Association between changes in molecular biomarkers of cartilage matrix turnover and changes in knee articular cartilage: a longitudinal pilot study

An early detection of Osteoarthritis is urgently needed and still not possible until today. The aim of the study was to assess whether molecular biomarkers of cartilage turnover are associated with longitudina...

Authors: Heide Boeth, Peter C. Raffalt, Aoife MacMahon, A. Robin Poole, Felix Eckstein, Wolfgang Wirth, Frank Buttgereit, Patrik Önnerfjord, Pilar Lorenzo, Cecilia Klint, Anna Pramhed and Georg N. Duda

The role of the medial plate for Pauwels type III femoral neck fracture: a comparative mechanical study using two fixations with cannulated screws

The biomechanical behavior of Pauwels type III fractures should be taken into consideration when performing internal fixation, since this repair should resist the shear force inherent in the vertical fracture ...

Authors: Vincenzo Giordano, Danilo Diniz Alves, Roger Pletsch Paes, Arthur Bonfim Amaral, Marcos Giordano, William Belangero, Anderson Freitas, Hilton A. Koch and Ney Pecegueiro do Amaral

Biomechanical comparison of meniscus-suture constructs for pullout repair of medial meniscus posterior root tears

Transtibial pullout repair for posterior meniscus root tear is widely performed to restore meniscal function. However, it is sometimes technically difficult to pass the suture through the posterior medial meni...

Authors: Shinichiro Okimura, Tatsuo Mae, Yuta Tachibana, Ryo Iuchi, Ken Nakata, Toshihiko Yamashita and Konsei Shino

Absence of cytotoxic and inflammatory effects following in vitro exposure of chondrogenically-differentiated human mesenchymal stem cells to adenosine, lidocaine and Mg²⁺ solution

ALM solution, a combination of adenosine, lidocaine and Mg²⁺, is an emerging small volume therapy that has been shown to prevent and correct coagulopathy and surgery-related inflammation in preclinical models, th...

Authors: Andrew McCutchan, Geoffrey P. Dobson, Natalie Stewart, Hayley L. Letson, Andrea L. Grant, Ivana-Aleksandra Jovanovic, Kaushik Hazratwala, Matthew Wilkinson, Peter McEwen and Jodie Morris

Higher blood glucose and larger fluctuations detected postoperatively using continuous glucose monitoring: a preliminary study following total knee or hip arthroplasty

The control of diabetes mellitus (DM) should help reduce the incidence of periprosthetic joint infection (PJI). Self-monitoring of blood glucose (SMBG) concentration is usually undertaken at fixed time-points....

Authors: Yuki Maeda, Nobuo Nakamura, Takashi Tsujimoto and Nobuhiko Sugano

Effect on inclined medial proximal tibial articulation for varus alignment in advanced knee osteoarthritis

The inclination of the medial compartment of the proximal tibia (MCT) is assumed to be a critical factor for varus alignment in advanced knee osteoarthritis (OA). This study was aimed at investigating; (1) whe...

Authors: Tomoharu Mochizuki, Yoshio Koga, Osamu Tanifuji, Takashi Sato, Satoshi Watanabe, Hiroshi Koga, Koichi Kobayashi, Go Omori and Naoto Endo

Graft materials provide greater static strength to medial opening wedge high tibial osteotomy than when no graft is included

The purpose of this study was to compare the stability of medial opening-wedge high tibial osteotomy (MOWHTO) with and without different graft materials. Good clinical and radiological outcomes have been demon...

Authors: James Belsey, Arnaud Diffo Kaze, Simon Jobson, James Faulkner, Stefan Maas, Raghbir Khakha, Adrian J. Wilson and Dietrich Pape

Effects of season long participation on ACL volume in female intercollegiate soccer athletes

The aim of this study was to characterize the volumetric changes of the anterior cruciate ligament over the course of a competitive soccer season in female athletes.

Authors: Karen M. Myrick, Andreas Voss, Richard S. Feinn, Thomas Martin, Bernadette M. Mele and Juan C. Garbalosa

Influence of knee position and examiner-induced motion on the kinematics of the pivot shift

Grading of the pivot shift test varies significantly depending on the examiner’s technique. Thus, the purpose of this study was to determine the influence of knee starting position and the magnitude of motion ...

Authors: Jan-Hendrik Naendrup, Jason P. Zlotnicki, Conor I. Murphy, Neel K. Patel, Richard E. Debski and Volker Musahl

Biplane opening wedge high tibial osteotomy with a distal tuberosity osteotomy, radiological and clinical analysis with minimum follow-up of 2 years

High tibial osteotomy is an established and helpful treatment for unicompatimental osteoarthritis associated with varus deformity. However, asupratubercle high tibial osteotomy leads to a decrease in patellar ...

Authors: Juan Erquicia, Pablo Eduardo Gelber, Simone Perelli, Federico Ibañez, Maximiliano Ibañez, Xavier Pelfort and Juan Carlos Monllau

Advances in modern osteotomies around the knee

Corrective lower limb osteotomies are innovative and efficient therapeutic procedures for restoring axial alignment and managing unicompartmental knee osteoarthritis. This review presents critical insights int...

Authors: Liang Gao, Henning Madry, Dmitrii V. Chugaev, Matteo Denti, Aleksandr Frolov, Mikhail Burtsev, Nina Magnitskaya, Victor Mukhanov, Philippe Neyret, Leonid N. Solomin, Evgeniy Sorokin, Alex E. Staubli, Kevin R. Stone, Viktor Vilenskiy, Vitaliy Zayats, Dietrich Pape…

Influence of uncemented humeral stem proximal geometry on stress distributions and torsional stability following total shoulder arthroplasty

While surgeons tend to implant larger stems to improve torsional stability, numerous studies demonstrated that increasing humeral stem diameter could exacerbate stress-shielding and lead to bone resorption. We...

Authors: Johannes Barth, Jérôme Garret, Laurent Geais, Hugo Bothorel, Mo Saffarini and Arnaud Godenèche

Plantar pressure changes in hindfoot relief devices of different designs

It is frequently observed that overloading the foot can impair bone and soft tissue healing and can lead to harmful sequelae (i.e. ulcers, stress reactions) in context of pre-existing tissue disabilities. In t...

Authors: F. Mazur, B. Swoboda, H. D. Carl, C. Lutter, M. Engelhardt, M. W. Hoppe, T. Hotfiel and C. Grim

Evaluation kinaesthetic proprioceptive deficit after knee anterior cruciate ligament (ACL) reconstruction in athletes

The objective of this study was to evaluate kinaesthetic proprioceptive deficit after knee anterior cruciate ligament (ACL) reconstruction in two populations of athletes, those in the post-surgery period and t...

Authors: E. Laboute, E. Verhaeghe, O. Ucay and A. Minden

Knee biomechanics changes under dual task during single-leg drop landing

Authors: Masaya Kajiwara, Akihiro Kanamori, Hideki Kadone, Yusuke Endo, Yasuto Kobayashi, Kojiro Hyodo, Tatsuya Takahashi, Norihito Arai, Yu Taniguchi, Tomokazu Yoshioka and Masashi Yamazaki

Growth factor levels in leukocyte-poor platelet-rich plasma and correlations with donor age, gender, and platelets in the Japanese population

Clinical application of platelet-rich-plasma (PRP) has been accelerated to investigate early recovery from various musculoskeletal conditions. It involves the promotion of tissue damage repair through the acti...

Authors: Yu Taniguchi, Tomokazu Yoshioka, Hisashi Sugaya, Masahiko Gosho, Katsuya Aoto, Akihiro Kanamori and Masashi Yamazaki

Capsular plication in the non-deformity hip: impact on post-operative joint stability

The aim of this study was to evaluate the hip joint range of motion after different capsular plication. The study hypothesis proposed that capsular plication after hip arthroscopy may reduce hip external rotat...

Authors: Etienne L. Belzile, Mathieu Hébert, Nicolas Janelle, Benoit Lechasseur, Yoann Dessery, Olufemi R. Ayeni and Philippe Corbeil

Anatomic study of the medial side of the ankle base on the joint capsule: an alternative description of the deltoid and spring ligament

Adult acquired flatfoot deformity (AAFD) is caused by impaired medial ligamentous structures and posterior tibialis tendon dysfunction (PTTD). Although degeneration and trauma could separately cause AAFD, how ...

Authors: Kentaro Amaha, Akimoto Nimura, Reiko Yamaguchi, Natnicha Kampan, Atsushi Tasaki, Kumiko Yamaguchi, Ryuichi Kato and Keiichi Akita

The history of radiofrequency energy and Coblation in arthroscopy: a current concepts review of its application in chondroplasty of the knee

Radiofrequency energy has had widespread use for a variety of surgical procedures. Its application in orthopedic surgery initiated with shoulder instability. Over the last couple decades it has been applied as...

Authors: Scott R. Anderson, Scott C. Faucett, David C. Flanigan, Ralph A. Gmabardella and Nirav H. Amin

Effect of geometric variations on tibiofemoral surface and post-cam design of normal knee kinematics restoration

Restoration of natural knee kinematics for a designed mechanism in knee implants is required to achieve full knee function in total knee arthroplasty (TKA). In different posterior-stabilized TKAs, there are wi...

Authors: Yong-Gon Koh, Ji-Hoon Nam and Kyoung-Tak Kang

Autologous micro-fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis: an update at 3 year follow-up

Conservative therapies for the treatment of knee degenerative processes are used before resorting to surgery; nonetheless, they may offer only short-term benefits. Encouraging preliminary results have been rep...

Authors: A. Russo, D. Screpis, S. L. Di Donato, S. Bonetti, G. Piovan and C. Zorzi

Biomechanical evaluation of two minimal access interbody cage designs in a cadaveric model

Different interbody grafts have been employed and evaluated for spinal fusion surgery. The Memory Metal Minimal Access Cage (MAC) is a hollow horseshoe shaped interbody fusion concept which provides a potentia...

Authors: D. Kok, C. M. M. Peeters, F. H. Wapstra, S. K. Bulstra and A. G. Veldhuizen