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  1. Research

    Three-dimensional analysis of the tibial resection plane relative to the arthritic tibial plateau in total knee arthroplasty

    Kinematically aligned total knee arthroplasty strives to correct the arthritic deformity by restoring the native tibial joint line. However, the precision of such surgical correction needs to be quantified in ...

    J. Michael Johnson, Mohamed R. Mahfouz, Mehmet Rüştü Midillioğlu, Alexander J. Nedopil and Stephen M. Howell

    Journal of Experimental Orthopaedics 2017 4:27

    Published on: 8 August 2017

  2. Research

    Tendon end separation with loading in an Achilles tendon repair model: comparison of non-absorbable vs. absorbable sutures

    Rupture of the Achilles tendon often leads to long-term morbidity, particularly calf weakness associated with tendon elongation. Operative repair of Achilles tendon ruptures leads to reduced tendon elongation....

    Michael R. Carmont, Jan Herman Kuiper, Karin Grävare Silbernagel, Jón Karlsson and Katarina Nilsson-Helander

    Journal of Experimental Orthopaedics 2017 4:26

    Published on: 21 July 2017

  3. Research

    The biochemical and histological analysis of subcutaneous calcitonin and intramedullary methylprednisolone on bone repair after bone marrow ablation: an experimental comparative study in rats

    Although, glucocorticoid (GC) and calcitonin-induced changes in bone repair have been studied previously, the exact effects of these on fracture healing remain controversial. Hence, the purpose of this experim...

    Salim Ersozlu, Bartu Sarisozen, Ozgur Ozer, Saduman Balaban Adim and Orcun Sahin

    Journal of Experimental Orthopaedics 2017 4:25

    Published on: 20 July 2017

  4. Research

    Varus-valgus instability in the anterior cruciate ligament-deficient knee: effect of posterior tibial load

    Anterior cruciate ligament (ACL) injury is often accompanied with medial collateral ligament (MCL) injury. Assessment of varus-valgus (V-V) instability in the ACL-deficient knee is crucial for the management o...

    Tomoki Ohori, Tatsuo Mae, Konsei Shino, Yuta Tachibana, Hiromichi Fujie, Hideki Yoshikawa and Ken Nakata

    Journal of Experimental Orthopaedics 2017 4:24

    Published on: 27 June 2017

  5. Research

    Mechanical strength assessment of a drilled hole in the contralateral cortex at the end of the open wedge for high tibial osteotomy

    This study aimed to investigate, by means of finite element analysis, the effect of a drill hole at the end of a horizontal osteotomy to reduce the risk of lateral cortex fracture while performing an opening w...

    Arnaud Diffo Kaze, Stefan Maas, Alexander Hoffmann and Dietrich Pape

    Journal of Experimental Orthopaedics 2017 4:23

    Published on: 23 June 2017

  6. Research

    Impact of mechanical stimulation on the chondrogenic processes in human bone marrow aspirates modified to overexpress sox9 via rAAV vectors

    Evaluation of gene-based approaches to target human bone marrow aspirates in conditions of mechanical stimulation that aim at reproducing the natural joint environment may allow to develop improved treatments ...

    Jagadeesh K. Venkatesan, Janina Frisch, Ana Rey-Rico, Gertrud Schmitt, Henning Madry and Magali Cucchiarini

    Journal of Experimental Orthopaedics 2017 4:22

    Published on: 21 June 2017

  7. Research

    Geometric morphometric analysis reveals age-related differences in the distal femur of Europeans

    Few studies have looked into age-related variations in femur shape. We hypothesized that three-dimensional (3D) geometric morphometric analysis of the distal femur would reveal age-related differences. The pur...

    Etienne Cavaignac, Frederic Savall, Elodie Chantalat, Marie Faruch, Nicolas Reina, Philippe Chiron and Norbert Telmon

    Journal of Experimental Orthopaedics 2017 4:21

    Published on: 12 June 2017

  8. Research

    Dynamic radiostereometric analysis for evaluation of hip joint pathomechanics

    Dynamic RSA (dRSA) enables non-invasive 3D motion-tracking of bones and may be used to evaluate in-vivo hip joint kinematics including hip pathomechanics such as femoroacetabular impingement (FAI) and the biom...

    Lars Hansen, Sepp de Raedt, Peter Bo Jørgensen, Bjarne Mygind-Klavsen, Bart Kaptein and Maiken Stilling

    Journal of Experimental Orthopaedics 2017 4:20

    Published on: 5 June 2017

  9. Research

    Autofluorescence imaging for improved visualization of joint structures during arthroscopic surgery

    The purpose of our study is to develop the arthroscopic autofluorescence imaging (AFI) system to improve the visualization during arthroscopic surgery by real-time enhancing the contrast between joint structur...

    Duy Tan Nguyen, Pepijn van Horssen, Hans Derriks, Martijn van de Giessen and Ton van Leeuwen

    Journal of Experimental Orthopaedics 2017 4:19

    Published on: 2 June 2017

  10. Review

    Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part I: biology, biomechanics, anatomy and an exercise-based approach

    Chronic tendinopathies represent a major problem in the clinical practice of sports orthopaedic surgeons, sports doctors and other health professionals involved in the treatment of athletes and patients that p...

    F. Abat, H. Alfredson, M. Cucchiarini, H. Madry, A. Marmotti, C. Mouton, J.M. Oliveira, H. Pereira, G. M. Peretti, D. Romero-Rodriguez, C. Spang, J. Stephen, C. J. A. van Bergen and L. de Girolamo

    Journal of Experimental Orthopaedics 2017 4:18

    Published on: 30 May 2017

  11. Research

    Does anatomic single-bundle ACL reconstruction using hamstring autograft produce anterolateral meniscal root tearing?

    To determine if tibial tunnel reaming during anatomic single-bundle anterior cruciate ligament (ACL) reconstruction using hamstring autograft can result in anterolateral meniscal root injury, as diagnosed by m...

    Sebastián Irarrázaval, Angel Masferrer-Pino, Maximiliano Ibañez, Tamer M. A. Shehata, María Naharro and Joan C. Monllau

    Journal of Experimental Orthopaedics 2017 4:17

    Published on: 22 May 2017

  12. Research

    The effect of repetitive flexion and extension fatigue loading on the young porcine lumbar spine, a feasibility study of MRI and histological analyses

    The biomechanical mechanisms of failure of FSUs have been studied but the correlation of repetitive flexion and extension loadings to the initial phase of fatigue in young FSUs are still not known. The purpose...

    Olof Thoreson, Lars Ekström, Hans-Arne Hansson, Carl Todd, Wisam Witwit, Anna Swärd Aminoff, Pall Jonasson and Adad Baranto

    Journal of Experimental Orthopaedics 2017 4:16

    Published on: 12 May 2017

  13. Research

    The rate of publication of free papers at the 2008 and 2010 European Society of Sports Traumatology Knee Surgery and Arthroscopy congresses

    The purpose of this study was to evaluate the frequency with which free papers presented at the 2008 and 2010 European Society of Sports Traumatology Knee Surgery and Arthroscopy (ESSKA) congress were ultimate...

    Jeffrey Kay, Muzammil Memon, Joelle Rogozinsky, Darren de SA, Nicole Simunovic, Romain Seil, Jon Karlsson and Olufemi Rolland Ayeni

    Journal of Experimental Orthopaedics 2017 4:15

    Published on: 10 May 2017

  14. Research

    Hyaluronan thiomer gel/matrix mediated healing of articular cartilage defects in New Zealand White rabbits—a pilot study

    Articular cartilage defects are limited to their regenerative potential in human adults. Our current study evaluates tissue regeneration in a surgically induced empty defect site with hyaluronan thiomer as a p...

    Christoph Bauer, Vivek Jeyakumar, Eugenia Niculescu-Morzsa, Daniela Kern and Stefan Nehrer

    Journal of Experimental Orthopaedics 2017 4:14

    Published on: 3 May 2017

  15. Research

    Three-dimensional geometric morphometric analysis reveals ethnic dimorphism in the shape of the femur

    Ethnic dimorphism in the distal femur has never been studied in a three-dimensional analysis focused on shape instead of size. Yet, this dimorphism has direct implications in orthopedic surgery and in anthropo...

    Etienne Cavaignac, Ke Li, Marie Faruch, Frederic Savall, Philippe Chiron, W. Huang and Norbert Telmon

    Journal of Experimental Orthopaedics 2017 4:13

    Published on: 2 May 2017

  16. Research

    The cytokine expression in synovial membrane and the relationship with pain and pathological findings at hip arthroscopy

    Synovial membrane inflammation is the most common finding presenting during hip arthroscopy, and may play a role in hip pain. We sought to determine the relationships between synovial cytokine levels, hip pain...

    Kensuke Fukushima, Gen Inoue, Hisako Fujimaki, Kentaro Uchida, Masayuki Miyagi, Naoshige Nagura, Katsufumi Uchiyama, Naonobu Takahira and Masashi Takaso

    Journal of Experimental Orthopaedics 2017 4:12

    Published on: 20 April 2017

  17. Short report

    A retinaculum-sparing surgical approach preserves porcine stifle joint cartilage in an experimental animal model of cartilage repair

    This study compares a traditional parapatellar retinaculum-sacrificing arthrotomy to a retinaculum-sparing arthrotomy in a porcine stifle joint as a cartilage repair model.

    Marcelo B. Bonadio, James M. Friedman, Mackenzie L. Sennett, Robert L. Mauck, George R. Dodge and Henning Madry

    Journal of Experimental Orthopaedics 2017 4:11

    Published on: 17 April 2017

  18. Research

    The effect of a dynamic PCL brace on patellofemoral compartment pressures in PCL-and PCL/PLC-deficient knees

    The natural history of posterior cruciate ligament (PCL) deficiency includes the development of arthrosis in the patellofemoral joint (PFJ). The purpose of this biomechanical study was to evaluate the hypothes...

    Tyler Welch, Thomas Keller, Ruben Maldonado, Melodie Metzger, Karen Mohr and Ronald Kvitne

    Journal of Experimental Orthopaedics 2017 4:10

    Published on: 31 March 2017

  19. Research

    Biomechanical cadaveric comparison of patellar ligament suture protected by a steel cable versus a synthetic cable

    Purpose and hypothesis: Patellar ligament rupture is a rare disabling pathology requiring a surgical ligament suture protected by a frame. The gold standard is the steel cable, but its rigidity and the necessi...

    P. Bouget, C. Breque, J. S. Beranger, J. P. Faure, F. Khiami and T. Vendeuvre

    Journal of Experimental Orthopaedics 2017 4:9

    Published on: 23 March 2017

  20. Research

    Different culture conditions affect the growth of human tendon stem/progenitor cells (TSPCs) within a mixed tendon cells (TCs) population

    Tendon resident cells (TCs) are a mixed population made of terminally differentiated tenocytes and tendon stem/progenitor cells (TSPCs). Since the enrichment of progenitors proportion could enhance the effecti...

    M. Viganò, C. Perucca Orfei, A. Colombini, D. Stanco, P. Randelli, V. Sansone and L. de Girolamo

    Journal of Experimental Orthopaedics 2017 4:8

    Published on: 28 February 2017

  21. Research

    Differences in biomarkers of cartilage matrix turnover and their changes over 2 years in adolescent and adult volleyball athletes

    This study aimed the feasibility to assess longitudinal changes in biomarkers of cartilage turnover and to determine their relationship with patient-rated outcomes over 2 years in volleyball athletes.

    Heide Boeth, Aoife MacMahon, A. Robin Poole, Frank Buttgereit, Patrik Önnerfjord, Pilar Lorenzo, Cecilia Klint, Anna Pramhed and Georg N. Duda

    Journal of Experimental Orthopaedics 2017 4:7

    Published on: 23 February 2017

  22. Research

    MRI findings of knee abnormalities in adolescent and adult volleyball players

    To longitudinally and cross-sectionally evaluate knee abnormalities by sex and age in adolescent and adult volleyball athletes over 2 years using magnetic resonance imaging (MRI).

    Heide Boeth, Aoife MacMahon, Felix Eckstein, Gerd Diederichs, Arne Schlausch, Wolfgang Wirth and Georg N. Duda

    Journal of Experimental Orthopaedics 2017 4:6

    Published on: 21 February 2017

  23. Research

    Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates

    Transplantation of genetically modified bone marrow concentrates is an attractive approach to conveniently activate the chondrogenic differentiation processes as a means to improve the intrinsic repair capacit...

    Ke Tao, Ana Rey-Rico, Janina Frisch, Jagadeesh Kumar Venkatesan, Gertrud Schmitt, Henning Madry, Jianhao Lin and Magali Cucchiarini

    Journal of Experimental Orthopaedics 2017 4:4

    Published on: 7 February 2017

  24. Review

    The haematoma and its role in bone healing

    Fracture treatment is an old endeavour intended to promote bone healing and to also enable early loading and regain of function in the injured limb. However, in today’s clinical routine the healing potential o...

    H. Schell, G. N. Duda, A. Peters, S. Tsitsilonis, K. A. Johnson and K. Schmidt-Bleek

    Journal of Experimental Orthopaedics 2017 4:5

    Published on: 7 February 2017

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