Abate M, Verna S, Schiavone C, Di Gregorio P, Salini V (2015) Efficacy and safety profile of a compound composed of platelet-rich plasma and hyaluronic acid in the treatment for knee osteoarthritis (preliminary results). Eur J Orthop Surg Traumatol 25:1321–1326
Article
PubMed
Google Scholar
Anandacoomarasamy A, March L (2010) Current evidence for osteoarthritis treatments. Ther Adv Musculoskelet Dis 2:17–28
Article
CAS
PubMed
PubMed Central
Google Scholar
Andia I, Abate M (2014) Knee osteoarthritis: hyaluronic acid, platelet-rich plasma or both in association? Expert Opin Biol Ther 14:635–649
Article
CAS
PubMed
Google Scholar
Altman R, Bedi A, Manjoo A, Niazi F, Shaw P, Mease P (2018) Anti-inflammatory effects of intra-articular hyaluronic acid: a systematic review. Cartilage 10:43–52
Article
PubMed
PubMed Central
CAS
Google Scholar
Alves R, Grimalt R (2017) A review of platelet-rich plasma: history, biology, mechanism of action, and classification. Skin Appendage Disord 4:18–24
Article
PubMed
PubMed Central
Google Scholar
Baria M, Vasileff W, Borchers J, DiBartola A, Flanigan D, Plunkett E, Magnussen R (2021) Treating knee osteoarthritis with platelet-rich plasma and hyaluronic acid combination therapy: a systematic review. Am J Sports Med 363546521998010
Campbell K, Saltzman B, Mascarenhas R, Khair M, Verma N, Bach B, Cole B (2015) Does intra-articular platelet-rich plasma injection provide clinically superior outcomes compared with other therapies in the treatment of knee osteoarthritis? A systematic review of overlapping Meta-analyses. Arthroscopy 31:2213–2221
Article
PubMed
Google Scholar
Chen W, Lo W, Hsu W, Wei H, Liu H, Lee C, Tina Chen S, Shieh Y, Williams D, Deng W (2014) Synergistic anabolic actions of hyaluronic acid and platelet-rich plasma on cartilage regeneration in osteoarthritis therapy. Biomaterials 35:9599–9607
Article
CAS
PubMed
Google Scholar
Cui A, Li H, Wang D, Zhong J, Chen Y, Lu H (2020) Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies. EClinicalMedicine 29-30:100587
Article
PubMed
PubMed Central
Google Scholar
Daheshia M, Yao J (2008) The interleukin 1β pathway in the pathogenesis of osteoarthritis. J Rheumatol 35:2306–2312
Article
CAS
PubMed
Google Scholar
Dhurat R, Sukesh M (2014) Principles and methods of preparation of platelet-rich plasma: a review and author′s perspective. J Cutan Aesthet Surg 7:189
Article
PubMed
PubMed Central
Google Scholar
Ding Q, Lv S, Shen X, Tong P (2017) A prospective randomized controlled study on platelet-rich plasma (PRP) combined with sodium hyaluronate (HA) intra-articular injection in the treatment of knee osteoarthritis. Shanghai Med Pharmaceut J 38(5):25–28
Google Scholar
Dohan Ehrenfest David M (2014) Classification of platelet concentrates (platelet-rich plasma-PRP, platelet-rich fibrin-PRF) for topical and infiltrative use in orthopedic and sports medicine: current consensus, clinical implications and perspectives. Muscles Ligaments Tendons J 4(1):3–9
Article
CAS
PubMed
PubMed Central
Google Scholar
Fadadu P, Mazzola A, Hunter C, Davis T (2019) Review of concentration yields in commercially available platelet-rich plasma (PRP) systems: a call for PRP standardization. Reg Anesthesia Pain Med 44:652–659
Article
Google Scholar
Filardo G, Di Matteo B, Di Martino A, Merli M, Cenacchi A, Fornasari P, Marcacci M, Kon E (2015) Platelet-rich plasma intra-articular knee injections show no superiority versus viscosupplementation. Am J Sports Med 43:1575–1582
Article
PubMed
Google Scholar
Filard G, Kon E, Di Martino A, Di Matteo B, Merli M, Cenacchi A, Fornasari P, Marcacci (2012) Platelet-rich plasma vs hyaluronic acid to treat knee degenerative pathology: study design and preliminary results of a randomized controlled trial. BMC Musculoskelet Disord 13(1):229
Article
CAS
Google Scholar
Guo Y, Yu H, Yong M et al (2018) Treatment of knee osteoarthritis with mixture of platelet-rich-plasma plus hyaluronic acid. Chin J Joint Surg (Electronic Edition) 12:874–878
Google Scholar
Guo Y, Yu H, Yuan L (2016) Treatment of knee osteoarthritis with platelet-rich plasma plus hyaluronic acid in comparison with platelet-rich plasma only. Int J Clin Exp Med 9(6):12085–12090
CAS
Google Scholar
Hermans J, Bierma-Zeinstra S, Bos P, Niesten D, Verhaar J, Reijman M (2019) The effectiveness of high molecular weight hyaluronic acid for knee osteoarthritis in patients in the working age: a randomised controlled trial. BMC Musculoskelet Disord 20:196
Article
PubMed
PubMed Central
Google Scholar
Hsu H. Knee Osteoarthritis. StatPearls. https://www.ncbi.nlm.nih.gov/books/NBK507884/. Published June 29, 2020. Accessed 15 Jan 2021
Jacob G, Shetty V, Shetty S (2017) A study assessing intra-articular PRP vs PRP with HMW HA vs PRP with LMW HA in early knee osteoarthritis. J Arthrosc Jt Surg 4:65–71
Article
Google Scholar
Ke C, Zhang R, Xue J (2016) Clinical efficacy of autologous platelet-rich plasma combined with intra-articular hyaluronic acid injection for knee osteoarthritis. Chin Gen Pract 14:1810–1812
Google Scholar
Kennedy M, Whitney K, Evans T, LaPrade R (2018) Platelet-rich plasma and cartilage repair. Curr Rev Musculoskelet Med 11:573–582
Article
PubMed
PubMed Central
Google Scholar
Kon E, Di Matteo B, Delgado D, Cole B, Dorotei A, Dragoo J, Filardo G, Fortier L, Giuffrida A, Jo C, Magalon J, Malanga G, Mishra A, Nakamura N, Rodeo S, Sampson S, Sánchez M (2020) Platelet-rich plasma for the treatment of knee osteoarthritis: an expert opinion and proposal for a novel classification and coding system. Expert Opin Biol Ther 20:1447–1460
Article
CAS
PubMed
Google Scholar
Lana H, Weglein A, Sampson S, Vicente E, Huber S, Souza C, Ambach M, Vincent H, Urban-paffaro A, Onodera C, Annichino-bizzacchi J, Santana M, Belangero W (2016) Randomized controlled trial comparing hyaluronic acid, platelet-rich plasma and the combination of both in the treatment of mild and moderate osteoarthritis of the knee. J Stem Cells Regen Med 12:69–78
Article
PubMed
PubMed Central
Google Scholar
Mautner K, Malanga G, Smith J, Shiple B, Ibrahim V, Sampson S, Bowen J (2015) A call for a standard classification system for future biologic research: the rationale for new PRP nomenclature. PM&R 7:S53–S59
Article
Google Scholar
Moussa M, Lajeunesse D, Hilal G, El Atat O, Haykal G, Serhal R, Chalhoub A, Khalil C, Alaaeddine N (2017) Platelet rich plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic cartilage. Exp Cell Res 352:146–156
Article
CAS
PubMed
Google Scholar
Palco M, Fenga D, Basile GC, Rizzo P, Cavalieri B, Leonetti D et al (2021) Platelet-rich plasma combined WITH hyaluronic ACID versus leucocyte and platelet-rich plasma in the conservative treatment of knee osteoarthritis. A retrospective study. Medicina 57(3):232
Article
PubMed
PubMed Central
Google Scholar
Patel S, Dhillon M, Aggarwal S, Marwaha N, Jain A (2013) Treatment with platelet-rich plasma is more effective than placebo for knee osteoarthritis. Am J Sports Med 41:356–364
Article
PubMed
Google Scholar
Rabi’u M, Aliyu D (2019) Effect of addition of hyaluronic acid on platelet rich plasma in treatment of chronic osteoarthritis. EAS J Orthop Physiother 1:63–67
Google Scholar
Rahman M, Islam S, Hossain M, Arefin M, Islam M, Begum S, Shompa S, Akhtaruzzaman A (2019) Effects of platelet rich plasma in combination with hyaluronic acid in the treatment of primary knee osteoarthritis. J Natl Inst Neurosci Bangladesh 5(2):137–142
Article
Google Scholar
Rodeo S (2019) The need for minimum reporting standards for studies of “biologics” in sports medicine. Am J Sports Med 47(11):2531–2532
Article
PubMed
Google Scholar
Rossi L, Murray I, Chu C, Muschler G, Rodeo S, Piuzzi N (2019) Classification systems for platelet-rich plasma. Bone Joint J 101-B:891–896
Article
CAS
PubMed
Google Scholar
Sánchez M, Fiz N, Azofra J, Usabiaga J, Aduriz Recalde E, Garcia Gutierrez A, Albillos J, Gárate R, Aguirre J, Padilla S, Orive G, Anitua E (2012) A randomized clinical trial evaluating plasma rich in growth factors (PRGF-Endoret) versus hyaluronic acid in the short-term treatment of symptomatic knee osteoarthritis. Arthroscopy 28:1070–1078
Article
PubMed
Google Scholar
Smith P (2016) Intra-articular autologous conditioned plasma injections provide safe and efficacious treatment for knee osteoarthritis. Am J Sports Med 44:884–891
Article
PubMed
Google Scholar
Sowers M, Karvonen-Gutierrez C (2010) The evolving role of obesity in knee osteoarthritis. Curr Opin Rheumatol 22:533–537
Article
PubMed
PubMed Central
Google Scholar
Sun SF, Lin GC, Hsu C et al (2021) Comparing efficacy of intraarticular single crosslinked Hyaluronan (HYAJOINT Plus) and platelet-rich plasma (PRP) versus PRP alone for treating knee osteoarthritis. Sci Rep 11:140
Article
CAS
PubMed
PubMed Central
Google Scholar
Sundman E, Cole B, Karas V, Della Valle C, Tetreault M, Mohammed H, Fortier L (2013) The anti-inflammatory and matrix restorative mechanisms of platelet-rich plasma in osteoarthritis. Am J Sports Med 42:35–41
Article
PubMed
Google Scholar
Tamer T (2013) Hyaluronan and synovial joint: function, distribution and healing. Interdiscip Toxicol 6:111–125
Article
PubMed
PubMed Central
CAS
Google Scholar
Vaquerizo V, Plasencia M, Arribas I, Seijas R, Padoilla S, Orive G, Anitua E (2013) Comparison of intra-articular injections of plasma rich in growth factors (PRGF-Endoret) versus durolane hyaluronic acid in the treatment of patients with symptomatic osteoarthritis: a randomized controlled trial. Arthroscopy 29:1635–1643
Article
PubMed
Google Scholar
Xu Z, He Z, Shu L, Li X, Ma M, Ye C (2021) Intra-articular platelet-rich plasma combined with hyaluronic acid injection for knee osteoarthritis is superior to platelet-rich plasma or hyaluronic acid alone in inhibiting inflammation and improving pain and function. Arthroscopy: J Arthrosc Related Surg 37(3):903–915
Article
Google Scholar
Yu W, Xu P, Huang G, Liu L (2018) Clinical therapy of hyaluronic acid combined with platelet-rich plasma for the treatment of knee osteoarthritis. Exp Ther Med 16(3):2119–2125
PubMed
PubMed Central
Google Scholar
Zhang Y, Jordan J (2010) Epidemiology of osteoarthritis. Clin Geriatr Med 26:355–369
Article
PubMed
PubMed Central
Google Scholar
Zhao J, Huang H, Liang G, Zeng L, Yang W, Liu J (2020) Effects and safety of the combination of platelet-rich plasma (PRP) and hyaluronic acid (HA) in the treatment of knee osteoarthritis: a systematic review and meta-analysis. BMC Musculoskelet Disord 21(1):224
Article
CAS
PubMed
PubMed Central
Google Scholar
Zhao X (2018) Clinical effect of sodium hyaluronate injection combined with autologous platelet rich plasma injection for knee osteoarthritis. Clin Res Pract 3(25):27–28
Google Scholar