Skip to main content

Table 1 detailing the characteristics of the included studies

From: Comparing the efficacy of dual Platelet-Rich Plasma (PRP) and Hyaluronic Acid (HA) therapy with PRP-alone therapy in the treatment of knee osteoarthritis: a systematic review and meta-analysis

First Author, Year Study design Language Total number of patients Number of patients Age Gender
(F:M)
Kellgren-Lawrence Score
(I:II:III:IV)
Follow-up period Outcomes reported
PRP + HA PRP PRP + HA PRP PRP + HA PRP PRP + HA PRP
Ding, 2017 [12] RCT Chinese 47 27 20 56.75 ± 9.54 62.11 ± 12.5 18:2 19:8 9:6:5:0 10:11:6:0 6 months VAS, WOMAC, Lequesne
Zhao, 2018 [45] RCT Chinese 124 62 62 55.73 ± 7.18 56.32 ± 8.13 27:35 25:37 5 weeks VAS, JOA
Ke, 2016 [22] RCT Chinese 150 50 50 57.80 ± 6.90 59.30 ± 7.10 25:25 26:24 5:11:20:14 6:12:20:12 12 months WOMAC, IKDC, Lequesne
Guo, 2018 [17] RCT Chinese 126 63 63 61.00 ± 10.00 61.00 ± 10.00 18:45 12:51 17:28:18:0 15:31:17:0 12 months VAS, WOMAC
Abate, 2015 [1] Retrospective cohort English 80 40 40 56.70 ± 11.20 60.90 ± 9.00 9:31 19:21 0:23:17:0 0:19:21:0 6 months VAS, KOOS
Guo, 2016 [18] Retrospective cohort English 126 63 63 61.20 ± 9.60 60.70 ± 10.10 45:18 51:12 17:28:18:0 15:31:17:0 12 months VAS, WOMAC
Jacob, 2017 [21] RCT English 51 20 31 6 months VAS, IKDC
Yu, 2018 [42] RCT English 360 104 96 46.50 ± 7.50 46.20 ± 8.60 46:50 54:50 12 months WOMAC
Palco, 2021 [28] Retrospective cohort English 51 28 23 62.71 ± 7.88 54.04 ± 10.4 16:12 11:12 0:8:20:0 0:10:13:0 12 months VAS, KSS, KOOS
Sun, 2021 [37] RCT English 78 39 39 60.6 ± 8.4 58.4 ± 8.1 18:21 22:17 0:39:0:0 0:39:0:0 6 months VAS, WOMAC, Lequesne, SLS