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  1. Research

    Different culture conditions affect the growth of human tendon stem/progenitor cells (TSPCs) within a mixed tendon cells (TCs) population

    Tendon resident cells (TCs) are a mixed population made of terminally differentiated tenocytes and tendon stem/progenitor cells (TSPCs). Since the enrichment of progenitors proportion could enhance the effecti...

    M. Viganò, C. Perucca Orfei, A. Colombini, D. Stanco, P. Randelli, V. Sansone and L. de Girolamo

    Journal of Experimental Orthopaedics 2017 4:8

    Published on: 28 February 2017

  2. Research

    Differences in biomarkers of cartilage matrix turnover and their changes over 2 years in adolescent and adult volleyball athletes

    This study aimed the feasibility to assess longitudinal changes in biomarkers of cartilage turnover and to determine their relationship with patient-rated outcomes over 2 years in volleyball athletes.

    Heide Boeth, Aoife MacMahon, A. Robin Poole, Frank Buttgereit, Patrik Önnerfjord, Pilar Lorenzo, Cecilia Klint, Anna Pramhed and Georg N. Duda

    Journal of Experimental Orthopaedics 2017 4:7

    Published on: 23 February 2017

  3. Research

    MRI findings of knee abnormalities in adolescent and adult volleyball players

    To longitudinally and cross-sectionally evaluate knee abnormalities by sex and age in adolescent and adult volleyball athletes over 2 years using magnetic resonance imaging (MRI).

    Heide Boeth, Aoife MacMahon, Felix Eckstein, Gerd Diederichs, Arne Schlausch, Wolfgang Wirth and Georg N. Duda

    Journal of Experimental Orthopaedics 2017 4:6

    Published on: 21 February 2017

  4. Research

    Effects of combined rAAV-mediated TGF-β and sox9 gene transfer and overexpression on the metabolic and chondrogenic activities in human bone marrow aspirates

    Transplantation of genetically modified bone marrow concentrates is an attractive approach to conveniently activate the chondrogenic differentiation processes as a means to improve the intrinsic repair capacit...

    Ke Tao, Ana Rey-Rico, Janina Frisch, Jagadeesh Kumar Venkatesan, Gertrud Schmitt, Henning Madry, Jianhao Lin and Magali Cucchiarini

    Journal of Experimental Orthopaedics 2017 4:4

    Published on: 7 February 2017

  5. Review

    The haematoma and its role in bone healing

    Fracture treatment is an old endeavour intended to promote bone healing and to also enable early loading and regain of function in the injured limb. However, in today’s clinical routine the healing potential o...

    H. Schell, G. N. Duda, A. Peters, S. Tsitsilonis, K. A. Johnson and K. Schmidt-Bleek

    Journal of Experimental Orthopaedics 2017 4:5

    Published on: 7 February 2017

  6. Research

    Biomechanical testing of transcapsular meniscal repair

    All of previous biomechanical studies on meniscal repair have examined the meniscus itself without synovial membrane and capsule, although in the clinical setting, the meniscal repair is generally performed in...

    Ryo Iuchi, Tatsuo Mae, Konsei Shino, Tomohiko Matsuo, Hideki Yoshikawa and Ken Nakata

    Journal of Experimental Orthopaedics 2017 4:2

    Published on: 25 January 2017

  7. Research

    Patient perceptions regarding physician reimbursements, wait times, and out-of-pocket payments for anterior cruciate ligament reconstruction in Ontario

    Currently, there is a lack of knowledge regarding patient perceptions surrounding physician reimbursements, appropriate wait times, and out-of-pocket payment options for anterior cruciate ligament reconstructi...

    Muzammil Memon, Lydia Ginsberg, Darren de SA, Andrew Nashed, Nicole Simunovic, Mark Phillips, Matthew Denkers, Rick Ogilvie, Devin Peterson and Olufemi R. Ayeni

    Journal of Experimental Orthopaedics 2017 4:1

    Published on: 23 January 2017

  8. Research

    Drill wobble – effect on femoral tunnel aperture during anterior cruciate ligament reconstruction

    In anterior cruciate ligament reconstruction performed using cortical button fixation on the femur, we have observed a “wobble” effect that can occur when a cannulated femoral drill is used over a guide pin th...

    Naser Alnusif, Adam Hart, Maher Baroudi, Robert Marien, Mark Burman and Paul A. Martineau

    Journal of Experimental Orthopaedics 2016 3:37

    Published on: 12 December 2016

  9. Research

    Anatomical study: comparing the human, sheep and pig knee meniscus

    Animal models are commonly used in investigating new treatment options for knee joint injuries including injuries to the meniscus. The reliability and applicability of these models to replicate findings in hum...

    Talal Takroni, Leila Laouar, Adetola Adesida, Janet A. W. Elliott and Nadr M. Jomha

    Journal of Experimental Orthopaedics 2016 3:35

    Published on: 7 December 2016

  10. Research

    Randomized controlled trial comparing the effectiveness of the ultrasound-guided galvanic electrolysis technique (USGET) versus conventional electro-physiotherapeutic treatment on patellar tendinopathy

    Patellar tendinopathy has a high prevalence rate among athletes. Different therapeutic options can be found in the current literature, but none of them has been clearly established as the gold standard. The pu...

    F. Abat, J. L. Sánchez-Sánchez, A. M. Martín-Nogueras, J. I. Calvo-Arenillas, J. Yajeya, R. Méndez-Sánchez, J. C. Monllau and P. E. Gelber

    Journal of Experimental Orthopaedics 2016 3:34

    Published on: 16 November 2016

  11. Review

    Bone marrow aspirate concentrate for the treatment of osteochondral lesions of the talus: a systematic review of outcomes

    The goal of this perform a systematic review on the outcomes of bone marrow aspirate concentrate (BMAC) for the treatment of chondral defects and osteoarthritis (OA) of the talus.

    Jorge Chahla, Mark E. Cinque, Jason M. Schon, Daniel J. Liechti, Lauren M. Matheny, Robert F. LaPrade and Thomas O. Clanton

    Journal of Experimental Orthopaedics 2016 3:33

    Published on: 4 November 2016

    The Erratum to this article has been published in Journal of Experimental Orthopaedics 2016 3:38

  12. Review

    Knee donor-site morbidity after mosaicplasty – a systematic review

    Mosaicplasty has been associated with good short- to long-term results. Nevertheless, the osteochondral harvesting is restricted to the donor-site area available and it may lead to significant donor-site morbi...

    Renato Andrade, Sebastiano Vasta, Rogério Pereira, Hélder Pereira, Rocco Papalia, Mustafa Karahan, J. Miguel Oliveira, Rui L. Reis and João Espregueira-Mendes

    Journal of Experimental Orthopaedics 2016 3:31

    Published on: 3 November 2016

  13. Research

    New insight in the architecture of the quadriceps tendon

    Published data regarding the structure of the quadriceps tendon are diverse. Dissection of the quadriceps muscle group revealed that beside the rectus femoris, vastus lateralis, vastus intermedius and vastus m...

    Karl Grob, Mirjana Manestar, Luis Filgueira, Timothy Ackland, Helen Gilbey and Markus S. Kuster

    Journal of Experimental Orthopaedics 2016 3:32

    Published on: 3 November 2016

  14. Research

    Inflammatory cytokine levels in synovial fluid 3, 4 days postoperatively and its correlation with early-phase functional recovery after anterior cruciate ligament reconstruction: a cohort study

    Synovial fluid was collected prior to and at 3 to 4 days after ACL reconstruction to investigate the correlation between inflammatory cytokine levels in the acute phase after surgery and physical functional re...

    Makiko Inoue, Takeshi Muneta, Miyoko Ojima, Kaori Nakamura, Hideyuki Koga, Ichiro Sekiya, Mutsumi Okazaki and Kunikazu Tsuji

    Journal of Experimental Orthopaedics 2016 3:30

    Published on: 2 November 2016

  15. Research

    Knee joint kinematics with dynamic augmentation of primary anterior cruciate ligament repair - a biomechanical study

    Dynamic augmentation of anterior cruciate ligament tears seems to reduce anteroposterior knee translation close to the pre-injury level. The aim of the present study is to biomechanically investigate the cours...

    Janosch Häberli, Philipp Henle, Yves P. Acklin, Ivan Zderic and Boyko Gueorguiev

    Journal of Experimental Orthopaedics 2016 3:29

    Published on: 26 October 2016

  16. Research

    Three-dimensional kinematic and kinetic analysis of knee rotational stability in ACL-deficient patients during walking, running and pivoting

    Anterior cruciate ligament (ACL) deficiency leads to altered stability of the knee. The purpose of this study was to compare the dynamic, rotational stability of the knee, expressed as rotational stiffness, be...

    Marie Bagger Bohn, Annemette Krintel Petersen, Dennis Brandborg Nielsen, Henrik Sørensen and Martin Lind

    Journal of Experimental Orthopaedics 2016 3:27

    Published on: 12 October 2016

  17. Research

    The cross-sectional shape of the fourfold semitendinosus tendon is oval, not round

    The looped side of the semitendinosus tendon (ST) graft (i.e., the side inserted into the femoral tunnel during anterior cruciate ligament reconstruction) appears to be oval rather than round. The purpose of t...

    Takeshi Oshima, Junsuke Nakase, Hitoaki Numata, Yasushi Takata and Hiroyuki Tsuchiya

    Journal of Experimental Orthopaedics 2016 3:28

    Published on: 12 October 2016

  18. Research

    Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration

    Biomaterial scaffolds that deliver growth factors such as recombinant human bone morphogenetic proteins-2 (rhBMP-2) have improved clinical bone tissue engineering by enhancing bone tissue regeneration. This ap...

    Yu-Chieh Chiu, Eliza L. Fong, Brian J. Grindel, Fred K. Kasper, Daniel A. Harrington and Mary C. Farach-Carson

    Journal of Experimental Orthopaedics 2016 3:25

    Published on: 6 October 2016

  19. Research

    Imaging the implant-soft tissue interactions in total knee arthroplasty

    In Total Knee Arthroplasty (TKA), residual pain may be secondary to soft tissue impingements, which are difficult to visualize around chromium-cobalt implants using medical imaging, so their interactions remai...

    Michel P. Bonnin, Tom Van Hoof, Arnoud De Kok, Matthias Verstraete, Catherine Van der Straeten, Mo Saffarini and Jan Victor

    Journal of Experimental Orthopaedics 2016 3:24

    Published on: 3 October 2016

    The Erratum to this article has been published in Journal of Experimental Orthopaedics 2016 3:26

  20. Meeting report

    Basic science of osteoarthritis

    Osteoarthritis (OA) is a prevalent, disabling disorder of the joints that affects a large population worldwide and for which there is no definitive cure. This review provides critical insights into the basic k...

    Magali Cucchiarini, Laura de Girolamo, Giuseppe Filardo, J. Miguel Oliveira, Patrick Orth, Dietrich Pape and Pascal Reboul

    Journal of Experimental Orthopaedics 2016 3:22

    Published on: 13 September 2016

  21. Research

    Augmented repair of radial meniscus tear with biomimetic electrospun scaffold: an in vitro mechanical analysis

    Large radial tears that disrupt the circumferential fibers of the meniscus are associated with reduced meniscal function and increased risk of joint degeneration. Electrospun fibrous scaffolds can mimic the to...

    Benjamin B. Rothrauff, Piya-on Numpaisal, Brian B. Lauro, Peter G. Alexander, Richard E. Debski, Volker Musahl and Rocky S. Tuan

    Journal of Experimental Orthopaedics 2016 3:23

    Published on: 13 September 2016

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