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  1. Despite substantial animal evidence, cell therapy in humans remains in its infancy. The purpose of this study was to examine the potential therapeutic effects and safety of cell therapy in the treatment of ten...

    Authors: Seyed Peyman Mirghaderi, Zahra Valizadeh, Kimia Shadman, Thibault Lafosse, Leila Oryadi-Zanjani, Mir Saeed Yekaninejad and Mohammad Hossein Nabian
    Citation: Journal of Experimental Orthopaedics 2022 9:85
  2. The aim of this study was to compare the following three analgesic methods after Total knee arthroplasty (TKA): intravenous patient-controlled analgesia (IV-PCA), continuous adductor canal block (C-ACB), and i...

    Authors: Sung Eun Kim, Hyuk-Soo Han, Myung Chul Lee and Du Hyun Ro
    Citation: Journal of Experimental Orthopaedics 2022 9:84
  3. The AMADEUS (Area Measurement And DEpth and Underlying Structures) scoring and grading system has been proposed for the MRI based evaluation of untreated focal chondral defects around the knee. The clinical pr...

    Authors: Tizian Heinz, Felix Meller, Karsten Sebastian Luetkens, Konstantin Horas, Thomas Schäfer, Maximilian Rudert, Stephan Reppenhagen and Manuel Weißenberger
    Citation: Journal of Experimental Orthopaedics 2022 9:83
  4. Anterior cruciate ligament (ACL) injuries are caused by both contact and non-contact injuries. However, it can be claimed that non-contact ones account approximately for 70% of all cases. Thus, several authors...

    Authors: Vito Gaetano Rinaldi, Robert Prill, Sonja Jahnke, Stefano Zaffagnini and Roland Becker
    Citation: Journal of Experimental Orthopaedics 2022 9:81
  5. Despite many protocols that have been proposed, there’s no consensus in the literature regarding the optimal rehabilitation program and return to sports (RTS) protocol following isolated meniscal repair. The a...

    Authors: Filippo Calanna, Victoria Duthon and Jacques Menetrey
    Citation: Journal of Experimental Orthopaedics 2022 9:80
  6. Dynamic Intraligamentary Stabilization (DIS) is a technique for the repair of acute anterior cruciate ligament (ACL) injuries. The purpose of this study was to investigate the potential challenges of ACL reco...

    Authors: Riccardo Cristiani, Caroline Mouton, Renaud Siboni, Charles Pioger and Romain Seil
    Citation: Journal of Experimental Orthopaedics 2022 9:79
  7. The aim of this systematic review was to update the knowledge on risk factors and prevention strategies for shoulder injuries in overhead sports with special emphasis on methodological quality.

    Authors: Matthias Wilhelm Hoppe, Joana Brochhagen, Thomas Tischer, Knut Beitzel, Romain Seil and Casper Grim
    Citation: Journal of Experimental Orthopaedics 2022 9:78
  8. Anterior cruciate ligament (ACL) repair has been recommended as a treatment principle for ACL tears. Several authors have advocated a potential role for primary repair techniques in the ACL decision tree. Howe...

    Authors: Sophie C. Eberlein, Vanessa Rodriguez, Andreas Hecker, Katharina Schürholz, Sufian S. Ahmad and Frank M. Klenke
    Citation: Journal of Experimental Orthopaedics 2022 9:77
  9. This study evaluates the use of the needle arthroscopy in anatomical reconstruction of the lateral ankle. We hypothesized that the needle arthroscopy would allow anatomical reconstruction to be performed under...

    Authors: R. Lopes, T. Noailles, G. Padiolleau, N. Bouguennec and T. D. Vieira
    Citation: Journal of Experimental Orthopaedics 2022 9:75
  10. Certain types of repetitive sub-maximal knee loading cause microfatigue damage in the human anterior cruciate ligament (ACL) that can accumulate to produce macroscopic tissue failure. However, monitoring the p...

    Authors: Jinhee Kim, So Young Baek, Stephen H. Schlecht, Mélanie L. Beaulieu, Lindsay Bussau, Junjie Chen, James A. Ashton-Miller, Edward M. Wojtys and Mark M. Banaszak Holl
    Citation: Journal of Experimental Orthopaedics 2022 9:74
  11. The outcome after ACL reconstruction (ACLR) is in general disappointing with unacceptable number of athletes that do not return to pre-injury level of sports, high re-injury rates, early development of osteoar...

    Authors: Alli Gokeler, Alberto Grassi, Roy Hoogeslag, Albert van Houten, Tim Lehman, Caroline Bolling, Matthew Buckthorpe, Grant Norte, Anne Benjaminse, Pieter Heuvelmans, Stefano Di Paolo, Igor Tak and Francesco Della Villa
    Citation: Journal of Experimental Orthopaedics 2022 9:73

    The Correction to this article has been published in Journal of Experimental Orthopaedics 2022 9:111

  12. Several cytokines and growth factors start and progress the destruction process of joint hyaline cartilage and fibrosis formation. Captopril is classified as an Angiotensin-converting enzyme inhibitor in which...

    Authors: Seyed Ali Hashemi, Ali Azad, Amirhossein Erfani, Reza Shahriarirad and Negar Azarpira
    Citation: Journal of Experimental Orthopaedics 2022 9:72
  13. Potential sources of inaccuracy in leg length discrepancy (LLD) measurements commonly arise due to postural malalignment during radiograph acquisition. Preoperative planning techniques for total hip arthroplas...

    Authors: Mohammed Nazmy Hamad, Isaac Livshetz, Anshum Sood, Michael Patetta, Mark H. Gonzalez and Farid A. Amirouche
    Citation: Journal of Experimental Orthopaedics 2022 9:71
  14. Arthroscopic isolated biceps tenotomy is a procedure successfully performed in patients with degenerative rotator cuff tears which offers good clinical results. With this article, we describe the technique of ...

    Authors: Claudio Rosso, Kushtrim Grezda and Philipp R. Heuberer
    Citation: Journal of Experimental Orthopaedics 2022 9:70
  15. Injectable connective tissue matrices (CTMs) may promote tendon healing, given their minimally invasive properties, structural and biochemical extracellular matrix components, and capacity to fill irregular sp...

    Authors: Yong Mao, Nikita John, Nicole M. Protzman, Adam Kuehn, Desiree Long, Raja Sivalenka, Radoslaw A. Junka, Anna Gosiewska, Robert J. Hariri and Stephen A. Brigido
    Citation: Journal of Experimental Orthopaedics 2022 9:69
  16. Intraoperative wound irrigation prior to closure during total joint arthroplasty (TJA) is an essential component of preventing infections and limiting health care system costs. While studies have shown the eff...

    Authors: Brandon E. Lung, Ryan Le, Kylie Callan, Maddison McLellan, Leo Issagholian, Justin Yi, William C. McMaster, Steven Yang and David H. So
    Citation: Journal of Experimental Orthopaedics 2022 9:67
  17. Favorable clinical results have been reported following high tibial osteotomy (HTO) for medial meniscus posterior root tear (MMPRT) in knees with varus alignment. However, the effect on the preoperative neutra...

    Authors: Junya Itou, Umito Kuwashima, Masafumi Itoh and Ken Okazaki
    Citation: Journal of Experimental Orthopaedics 2022 9:65
  18. The purpose of this study was to evaluate clinical and radiological results in patients operated for recurrent patellar instability with a surgical approach consisting of Insall proximal realignment with/witho...

    Authors: Per Arne Skarstein Waaler, Truls Jellestad, Trine Hysing-Dahl, Elise Elvehøy and Eivind Inderhaug
    Citation: Journal of Experimental Orthopaedics 2022 9:64
  19. The aim of this study was to evaluate the range of motion (ROM) at the shoulder joint before and after silent manipulation.

    Authors: Kieun Park, Masashi Matsuzaki, Mitsuji Okamoto, Akihiro Sakaki and Futoshi Ikuta
    Citation: Journal of Experimental Orthopaedics 2022 9:63
  20. The intra-operative use of tourniquets during Total Knee Arthroplasty (TKA) is common practice. The advantages of tourniquet use include decreased operating time and the creation of a bloodless visualisation f...

    Authors: A. A. Magan, O. Dunseath, P. Armonis, A. Fontalis, B. Kayani and F. S. Haddad
    Citation: Journal of Experimental Orthopaedics 2022 9:62
  21. There is a paucity of quality of life (QoL) assessments in studies evaluating patients treated for recurrent lateral patellar dislocation (LPD). The primary aim of this study was to investigate whether mental ...

    Authors: Peter Balcarek, Danko Dan Milinkovic, Alexander Zimmerer and Felix Zimmermann
    Citation: Journal of Experimental Orthopaedics 2022 9:60
  22. The purpose of the study is to compare the effects of total cold-water immersion to ice massage on muscle damage, performance, and delayed onset of muscle soreness.

    Authors: Mohammed Ali Fakhro, Fatima AlAmeen and Rim Fayad
    Citation: Journal of Experimental Orthopaedics 2022 9:59

    The Correction to this article has been published in Journal of Experimental Orthopaedics 2022 9:93

  23. The purpose of this finite element study was to compare bone and cement stresses and implant micromotions among all-polyethylene (PE) and hybrid glenoid components. The hypothesis was that, compared to all-PE ...

    Authors: Nicolas Bonnevialle, Julien Berhouet, Paul Pôtel, Jacobus Hendrik Müller and Arnaud Godenèche
    Citation: Journal of Experimental Orthopaedics 2022 9:58
  24. The term “pectoralis minor syndrome” refers to this constellation of symptoms that can occur when the pectoralis minor (Pm) is shortened and contracted. Release of the tendon of the Pm from the coracoid has been ...

    Authors: David Haeni, Natalia Martinez-Catalan, Ronda N. Esper, Eric R. Wagner, Bassem T. El Hassan and Joaquin Sanchez-Sotelo
    Citation: Journal of Experimental Orthopaedics 2022 9:57
  25. To determine within-patient fusion rates of chambers filled with bioactive glass versus autologous iliac crest bone on computed tomography (CT) following anterior lumbar interbody fusion (ALIF).

    Authors: Marc Szadkowski, Sami Bahroun, Ivan Aleksic, Michiel Vande Kerckhove, Sonia Ramos-Pascual, Mo Saffarini, Vincent Fière and Henri d’Astorg
    Citation: Journal of Experimental Orthopaedics 2022 9:56
  26. The aim of this retrospective study is to present the clinical results of open repair of gluteus medius and gluteus minimus tendon tears using the single-row suture anchor technique.

    Authors: Alexander Derksen, Eike Lonnemann, Stefan Budde, Onno Becker, Nils Wirries, Marco Haertlé and Henning Windhagen
    Citation: Journal of Experimental Orthopaedics 2022 9:55
  27. The aim of this study was to conduct a systematic scoping review of previous in vitro spine studies that used pig functional spinal units (FSU) as a model to gain an understanding of how different experimental...

    Authors: Jacob Hedlund, Lars Ekström and Olof Thoreson
    Citation: Journal of Experimental Orthopaedics 2022 9:54

    The Correction to this article has been published in Journal of Experimental Orthopaedics 2022 9:68

  28. To evaluate the clinical outcomes, MRI imaging and histological characteristics of biopsy samples of the tendon from patients in whom rotator cuff repair was previously performed with a bioinductive type I bov...

    Authors: Jorge Alberto Camacho-Chacon, Jorge Cuenca-Espierrez, Victor Roda-Rojo, Adrian Martin-Martinez, Jose Manuel Calderon-Meza, Ramiro Alvarez-Alegret and Carlos Martin-Hernandez
    Citation: Journal of Experimental Orthopaedics 2022 9:53
  29. Although pain phenotype affects clinical score in patients with knee osteoarthritis (OA), little information has been available on the relationship between pain phenotype and gait analysis. The purpose was to ...

    Authors: Kengo Harato, Yu Iwama, Kazuya Kaneda, Shu Kobayashi, Yasuo Niki and Takeo Nagura
    Citation: Journal of Experimental Orthopaedics 2022 9:52
  30. It is usually assumed that the severity of varus osteoarthritis (OA) of the knee is correlated with the axis deviation of the limb. Despite this, there is currently no clear radiographic definition to define a...

    Authors: William Colyn, A. Cleymans, L. Bruckers, R. Houben, K. Smeets and J. Bellemans
    Citation: Journal of Experimental Orthopaedics 2022 9:51
  31. Surgical reconstruction is the current standard for ACL rupture treatment in active individuals. Recently, there is renewed interest in primary repair of proximal ACL tears. Despite this, ACL biology and heali...

    Authors: Kenneth M. Lin, Harmen D. Vermeijden, Craig E. Klinger, Lionel E. Lazaro, Scott A. Rodeo, Jonathan P. Dyke, David L. Helfet and Gregory S. DiFelice
    Citation: Journal of Experimental Orthopaedics 2022 9:50
  32. Although it has been recognized that the medial meniscus extrusion (MME) leads to progressive cartilage loss and osteoarthritis (OA), about 20% of cases with MME had minor symptoms and poor progression of knee...

    Authors: Takuhei Kozaki, Daisuke Fukui, Ei Yamamoto, Daisuke Nishiyama, Manabu Yamanaka, Akimasa Murata and Hiroshi Yamada
    Citation: Journal of Experimental Orthopaedics 2022 9:49
  33. Posttraumatic fibular malunion alters ankle joint biomechanics and may lead to pain, stiffness, and premature osteoarthritis. The accurate restoration is key for success of reconstructive surgeries. The aim of...

    Authors: Anna-Katharina Calek, Sandro Hodel, Bettina Hochreiter, Arnd Viehöfer, Sandro Fucentese, Stephan Wirth and Lazaros Vlachopoulos
    Citation: Journal of Experimental Orthopaedics 2022 9:48
  34. Patients undergoing knee surgery are at high risk for deep vein thrombosis (DVT), which is infrequent but potentially life-threatening. It has not been identified how to efficiently detect high-risk DVT while ...

    Authors: Manabu Akagawa, Hiroaki Kijima, Yoshiaki Kimura, Hidetomo Saito, Kimio Saito, Ikuko Wakabayashi, Takeshi Kashiwagura and Naohisa Miyakoshi
    Citation: Journal of Experimental Orthopaedics 2022 9:47
  35. The aim of the study was to directly measure graft forces of an anterior cruciate ligament reconstruction (ACLR) and a lateral extra-articular tenodesis (LET) using the modified Lemaire technique in combined a...

    Authors: Raul Mayr, Maximilian Sigloch, Christian Coppola, Romed Hoermann, Alessandra Iltchev and Werner Schmoelz
    Citation: Journal of Experimental Orthopaedics 2022 9:45
  36. To compare the accuracy, inter- and intrarater reliability, and user-experience of manual and semi-automatic preoperative leg-alignment measurement planning software for high tibial osteotomy (HTO).

    Authors: Iris E. W. G. Laven, Femke F. Schröder, Feike de Graaff, J. Christiaan Rompen, Roy A. G. Hoogeslag and Albert H. van Houten
    Citation: Journal of Experimental Orthopaedics 2022 9:44
  37. Genu varum- a common symptom in achondroplasia- may lead to ankle valgus in children. Ankle valgus may be mitigated by tibiofibular synostosis, but this is not always the case. The mechanical environment aroun...

    Authors: Tariq Rahman, Geovanny Oleas-Santillan, Jinyong Wee and William G. Mackenzie
    Citation: Journal of Experimental Orthopaedics 2022 9:43
  38. A tourniquet is routinely used during total knee arthroplasty (TKA) to reduce intra-operative hemorrhage, though surgery without a tourniquet is becoming popular. To address concerns about the effect of blood ...

    Authors: Wardah Rafaqat, Sudhesh Kumar, Tashfeen Ahmad, Zul Qarnain, Khalid Saeed Khan and Riaz Hussain Lakdawala
    Citation: Journal of Experimental Orthopaedics 2022 9:42
  39. Greater femoral internal rotation (via anteversion or passive hip ROM) is associated with knee biomechanics thought to contribute to anterior cruciate ligament (ACL) injury, but it is unknown if femoral intern...

    Authors: Jennifer A. Hogg, Justin P. Waxman and Sandra J. Shultz
    Citation: Journal of Experimental Orthopaedics 2022 9:40
  40. Molecular processes in primary osteoblasts were analyzed in response to magnetic and electric field exposure to examine its potential impact on bone healing.

    Authors: Klaus H. Dittmann, Claus Mayer, Heribert Stephan, Christin Mieth, Michael Bonin, Beat Lechmann and H. Peter Rodemann
    Citation: Journal of Experimental Orthopaedics 2022 9:39
  41. The purpose of this study was to compare the medial meniscus (MM) degeneration, meniscus extrusion, and tibial joint inclination by using MRI to consider the pathogenesis of posterior root tear (PRT) in medial...

    Authors: Kosuke Hisashi, Takeshi Muneta, Yuji Kohno, Mana Sasaki, Junya Yamazaki, Haruhisa Hayashi, Hideyuki Koga and Toshiyuki Morito
    Citation: Journal of Experimental Orthopaedics 2022 9:38
  42. Anterior cruciate ligament rupture is associated with characteristic bone contusions in approximately 80% of patients, and these have been correlated with higher pain scores. Bone bruising may indicate joint d...

    Authors: Lukas G. Keil, Douglas S. Onuscheck, Lincoln F. Pratson II, Ganesh V. Kamath, Robert A. Creighton, Daniel B. Nissman, Brian G. Pietrosimone and Jeffrey T. Spang
    Citation: Journal of Experimental Orthopaedics 2022 9:37
  43. The use of a robotic arm has been well-described in the literature for the placement of pedicle screws in spine surgery as well as implants for sacroiliac joint fusion. There are no reports describing the use ...

    Authors: Jon B. Carlson, Jiyao Zou and Brandi Hartley
    Citation: Journal of Experimental Orthopaedics 2022 9:36