Articles

Absence of cytotoxic and inflammatory effects following in vitro exposure of chondrogenically-differentiated human mesenchymal stem cells to adenosine, lidocaine and Mg²⁺ solution

ALM solution, a combination of adenosine, lidocaine and Mg²⁺, is an emerging small volume therapy that has been shown to prevent and correct coagulopathy and surgery-related inflammation in preclinical models, th...

Authors: Andrew McCutchan, Geoffrey P. Dobson, Natalie Stewart, Hayley L. Letson, Andrea L. Grant, Ivana-Aleksandra Jovanovic, Kaushik Hazratwala, Matthew Wilkinson, Peter McEwen and Jodie Morris

Higher blood glucose and larger fluctuations detected postoperatively using continuous glucose monitoring: a preliminary study following total knee or hip arthroplasty

The control of diabetes mellitus (DM) should help reduce the incidence of periprosthetic joint infection (PJI). Self-monitoring of blood glucose (SMBG) concentration is usually undertaken at fixed time-points....

Authors: Yuki Maeda, Nobuo Nakamura, Takashi Tsujimoto and Nobuhiko Sugano

Effect on inclined medial proximal tibial articulation for varus alignment in advanced knee osteoarthritis

The inclination of the medial compartment of the proximal tibia (MCT) is assumed to be a critical factor for varus alignment in advanced knee osteoarthritis (OA). This study was aimed at investigating; (1) whe...

Authors: Tomoharu Mochizuki, Yoshio Koga, Osamu Tanifuji, Takashi Sato, Satoshi Watanabe, Hiroshi Koga, Koichi Kobayashi, Go Omori and Naoto Endo

Graft materials provide greater static strength to medial opening wedge high tibial osteotomy than when no graft is included

The purpose of this study was to compare the stability of medial opening-wedge high tibial osteotomy (MOWHTO) with and without different graft materials. Good clinical and radiological outcomes have been demon...

Authors: James Belsey, Arnaud Diffo Kaze, Simon Jobson, James Faulkner, Stefan Maas, Raghbir Khakha, Adrian J. Wilson and Dietrich Pape

Effects of season long participation on ACL volume in female intercollegiate soccer athletes

The aim of this study was to characterize the volumetric changes of the anterior cruciate ligament over the course of a competitive soccer season in female athletes.

Authors: Karen M. Myrick, Andreas Voss, Richard S. Feinn, Thomas Martin, Bernadette M. Mele and Juan C. Garbalosa

Influence of knee position and examiner-induced motion on the kinematics of the pivot shift

Grading of the pivot shift test varies significantly depending on the examiner’s technique. Thus, the purpose of this study was to determine the influence of knee starting position and the magnitude of motion ...

Authors: Jan-Hendrik Naendrup, Jason P. Zlotnicki, Conor I. Murphy, Neel K. Patel, Richard E. Debski and Volker Musahl

Biplane opening wedge high tibial osteotomy with a distal tuberosity osteotomy, radiological and clinical analysis with minimum follow-up of 2 years

High tibial osteotomy is an established and helpful treatment for unicompatimental osteoarthritis associated with varus deformity. However, asupratubercle high tibial osteotomy leads to a decrease in patellar ...

Authors: Juan Erquicia, Pablo Eduardo Gelber, Simone Perelli, Federico Ibañez, Maximiliano Ibañez, Xavier Pelfort and Juan Carlos Monllau

Advances in modern osteotomies around the knee

Corrective lower limb osteotomies are innovative and efficient therapeutic procedures for restoring axial alignment and managing unicompartmental knee osteoarthritis. This review presents critical insights int...

Authors: Liang Gao, Henning Madry, Dmitrii V. Chugaev, Matteo Denti, Aleksandr Frolov, Mikhail Burtsev, Nina Magnitskaya, Victor Mukhanov, Philippe Neyret, Leonid N. Solomin, Evgeniy Sorokin, Alex E. Staubli, Kevin R. Stone, Viktor Vilenskiy, Vitaliy Zayats, Dietrich Pape…

Influence of uncemented humeral stem proximal geometry on stress distributions and torsional stability following total shoulder arthroplasty

While surgeons tend to implant larger stems to improve torsional stability, numerous studies demonstrated that increasing humeral stem diameter could exacerbate stress-shielding and lead to bone resorption. We...

Authors: Johannes Barth, Jérôme Garret, Laurent Geais, Hugo Bothorel, Mo Saffarini and Arnaud Godenèche

Plantar pressure changes in hindfoot relief devices of different designs

It is frequently observed that overloading the foot can impair bone and soft tissue healing and can lead to harmful sequelae (i.e. ulcers, stress reactions) in context of pre-existing tissue disabilities. In t...

Authors: F. Mazur, B. Swoboda, H. D. Carl, C. Lutter, M. Engelhardt, M. W. Hoppe, T. Hotfiel and C. Grim

Evaluation kinaesthetic proprioceptive deficit after knee anterior cruciate ligament (ACL) reconstruction in athletes

The objective of this study was to evaluate kinaesthetic proprioceptive deficit after knee anterior cruciate ligament (ACL) reconstruction in two populations of athletes, those in the post-surgery period and t...

Authors: E. Laboute, E. Verhaeghe, O. Ucay and A. Minden

Knee biomechanics changes under dual task during single-leg drop landing

Authors: Masaya Kajiwara, Akihiro Kanamori, Hideki Kadone, Yusuke Endo, Yasuto Kobayashi, Kojiro Hyodo, Tatsuya Takahashi, Norihito Arai, Yu Taniguchi, Tomokazu Yoshioka and Masashi Yamazaki

Growth factor levels in leukocyte-poor platelet-rich plasma and correlations with donor age, gender, and platelets in the Japanese population

Clinical application of platelet-rich-plasma (PRP) has been accelerated to investigate early recovery from various musculoskeletal conditions. It involves the promotion of tissue damage repair through the acti...

Authors: Yu Taniguchi, Tomokazu Yoshioka, Hisashi Sugaya, Masahiko Gosho, Katsuya Aoto, Akihiro Kanamori and Masashi Yamazaki

Capsular plication in the non-deformity hip: impact on post-operative joint stability

The aim of this study was to evaluate the hip joint range of motion after different capsular plication. The study hypothesis proposed that capsular plication after hip arthroscopy may reduce hip external rotat...

Authors: Etienne L. Belzile, Mathieu Hébert, Nicolas Janelle, Benoit Lechasseur, Yoann Dessery, Olufemi R. Ayeni and Philippe Corbeil

Anatomic study of the medial side of the ankle base on the joint capsule: an alternative description of the deltoid and spring ligament

Adult acquired flatfoot deformity (AAFD) is caused by impaired medial ligamentous structures and posterior tibialis tendon dysfunction (PTTD). Although degeneration and trauma could separately cause AAFD, how ...

Authors: Kentaro Amaha, Akimoto Nimura, Reiko Yamaguchi, Natnicha Kampan, Atsushi Tasaki, Kumiko Yamaguchi, Ryuichi Kato and Keiichi Akita

The history of radiofrequency energy and Coblation in arthroscopy: a current concepts review of its application in chondroplasty of the knee

Radiofrequency energy has had widespread use for a variety of surgical procedures. Its application in orthopedic surgery initiated with shoulder instability. Over the last couple decades it has been applied as...

Authors: Scott R. Anderson, Scott C. Faucett, David C. Flanigan, Ralph A. Gmabardella and Nirav H. Amin

Effect of geometric variations on tibiofemoral surface and post-cam design of normal knee kinematics restoration

Restoration of natural knee kinematics for a designed mechanism in knee implants is required to achieve full knee function in total knee arthroplasty (TKA). In different posterior-stabilized TKAs, there are wi...

Authors: Yong-Gon Koh, Ji-Hoon Nam and Kyoung-Tak Kang

Autologous micro-fragmented adipose tissue for the treatment of diffuse degenerative knee osteoarthritis: an update at 3 year follow-up

Conservative therapies for the treatment of knee degenerative processes are used before resorting to surgery; nonetheless, they may offer only short-term benefits. Encouraging preliminary results have been rep...

Authors: A. Russo, D. Screpis, S. L. Di Donato, S. Bonetti, G. Piovan and C. Zorzi

Biomechanical evaluation of two minimal access interbody cage designs in a cadaveric model

Different interbody grafts have been employed and evaluated for spinal fusion surgery. The Memory Metal Minimal Access Cage (MAC) is a hollow horseshoe shaped interbody fusion concept which provides a potentia...

Authors: D. Kok, C. M. M. Peeters, F. H. Wapstra, S. K. Bulstra and A. G. Veldhuizen

Proximity of the neurovascular structures during all-inside lateral meniscal repair in children: a cadaveric study

Meniscal repair has become increasingly common in a pediatric and adolescent population. All-inside repair techniques are utilized more often given their ease of insertion and decreased operative time required...

Authors: Yi-Meng Yen, Peter D. Fabricant, Connor G. Richmond, Aleksei B. Dingel, Matthew D. Milewski, Henry B. Ellis, Philip L. Wilson, Stephanie W. Mayer, Theodore J. Ganley and Kevin G. Shea

Medial collateral ligament laxity in valgus knee deformity before and after medial closing wedge high tibial osteotomy measured with instrumented laxity measurements and patient reported outcome

Medial closing wedge high tibial osteotomy (CWHTO) for valgus deformity correction was first described by Coventry whom performed an additional reefing of the medial collateral ligament (MCL) to prevent instab...

Authors: W. A. M. van Lieshout, C. D. Martijn, B. T. J. van Ginneken and R. J. van Heerwaarden

Mechanical assessment of tripled hamstring tendon graft when using suspensory fixation for cruciate ligament reconstruction

Tripling semitendinosus tendon for ACL graft preparation facilitates creation of longer and thicker grafts. Our objective was to evaluate the mechanical difference between tripled tendon grafts, prepared by th...

Authors: I. Geethan, K. Santhosh Sahanand, P. R. Ashwin Vijay and David V. Rajan

Iodine contrast agents do not influence Platelet-Rich Plasma function at an early time point in vitro

Iodine contrast agents (ICAs) are routinely used by radiologists to help guide intra-articular infiltrations. The aim of this study was to assess the in vitro effects of ICA on platelet function of human autol...

Authors: B. Dallaudiere, A. Crombé, A. P. Gadeau, L. Pesquer, A. Peuchant, C. James and A. Silvestre

Accuracy and reliability of knee goniometry methods

Measuring knee range of motion is important in examination and as a post-operative outcome. It is therefore important that measurements are accurate. Knee angles can be measured by traditional goniometers, sma...

Authors: Graeme Ethan Hancock, Tracey Hepworth and Kevin Wembridge

Force measurement metrics for simulated elbow arthroscopy training

Elbow arthroscopy is a difficult surgical technique. Objective metrics can be used to improve safe and effective training in elbow arthroscopy. Force exerted on the elbow tissue during arthroscopy can be a mea...

Authors: Nick F. J. Hilgersom, Tim Horeman-Franse, Ronald L. A. W. Bleys, Denise Eygendaal, Michel P. J. van den Bekerom and Gabriëlle J. M. Tuijthof

Rehabilitation strategies for optimisation of functional recovery after major joint replacement

Exercise-based interventions applied before and after total hip and knee arthroplasty (THA and TKA, respectively) have been investigated for a number of years, based on the assumption that they will enhance po...

Authors: Thomas Bandholm, Thomas W. Wainwright and Henrik Kehlet

Lower limb injury prevention programs in youth soccer: a survey of coach knowledge, usage, and barriers

Participation in youth soccer carries a significant risk of injury, most commonly non-contact injuries of the lower extremity. A growing body of research supports the use of neuromuscular interventions by team...

Authors: Robin Mawson, Michael J Creech, Devin C Peterson, Forough Farrokhyar and Olufemi R Ayeni

A biomechanical comparison of all-inside cruciate ligament graft preparation techniques

The all-inside cruciate ligament graft preparation technique has become popular due to its utility in sparing a growing physis, preserving a tendon in ACL surgery, and/or reduction of pain. However, few studie...

Authors: Colter R Wichern, Kathryn C Skoglund, Joseph G O’Sullivan, Anora K Burwell, Joseph T Nguyen, Andrea Herzka and Jacqueline M Brady

Biomechanical properties of adjustable extracortical graft fixations in ACL reconstruction

Reliable biomechanical data about the strength of different tibial extracortical graft fixation devices is sparse. This biomechanical study compares the properties of tibial graft fixation in ACL reconstructio...

Authors: M. Ettinger, R. Karkosch, H. Horstmann, P. Savov, T. Calliess, T. Smith and M. Petri

Novel renal markers for the assessment of renal integrity in patients undergoing knee arthroplasty – a pilot study

The feasibility of novel kidney injury biomarkers in consecutive patients having total knee arthroplasty with local infiltration analgesia was evaluated.

Authors: Annika Piirainen, Jukka Huopio, Hannu Kokki, Anu Holopainen, Teemu Pajunen, Kari Pulkki and Merja Kokki

Discoid lateral meniscus in children and adolescents: a histological study

Discoid lateral meniscus is the most frequent variant of the meniscus. Although the histology of normal menisci in children and in adults has been well described, few studies have focused on the histology of d...

Authors: Salvatore Bisicchia, Flavia Botti and Cosimo Tudisco

Current trends in tendinopathy: consensus of the ESSKA basic science committee. Part II: treatment options

The treatment of painful chronic tendinopathy is challenging. Multiple non-invasive and tendon-invasive methods are used. When traditional non-invasive treatments fail, the injections of platelet-rich plasma a...

Authors: F. Abat, H. Alfredson, M. Cucchiarini, H. Madry, A. Marmotti, C. Mouton, J. M. Oliveira, H. Pereira, G. M. Peretti, C. Spang, J. Stephen, C. J. A. van Bergen and L. de Girolamo

Evaluation of dynamic change in regenerated tendons in a mouse model

Using the film model method, the process whereby a substance called tendon gel is secreted from transected tendon ends and changed into a tendon after application of a traction force is known. The objective of...

Authors: Yoshinori Ohashi, Junsuke Nakase, Kengo Shimozaki, Kojun Torigoe and Hiroyuki Tsuchiya

Novel preclinical murine model of trauma-induced elbow stiffness

Peri-articular injury may result in functional deficits and pain. In particular, post-traumatic elbow stiffness is a debilitating condition, precluding patients from performing activities of daily living. As s...

Authors: Stephanie N. Moore-Lotridge, William K. Oelsner, Yael Ihejirika, Mihir J. Desai, Sandra S. Gebhart and Jonathan G. Schoenecker

Is global humeral head offset related to intramedullary canal width? A computer tomography morphometric study

While most anatomic TSA stems allow some intra-operative adjustments, the default configuration assumes that head offset is directly proportional to stem diameter. Some authors reported that humeral head diame...

Authors: Johannes Barth, Jérôme Garret, Achilleas Boutsiadis, Etienne Sautier, Laurent Geais, Hugo Bothorel and Arnaud Godenèche

A cadaveric model to evaluate the effect of unloading the medial quadriceps on patellar tracking and patellofemoral joint pressure and stability

Vastus Medialis Muscles (VMM) damage has been widely identified following patellar dislocation. Rehabilitation programmes have been suggested to strengthen the VMM and reduce clinical symptoms of pain and inst...

Authors: Joanna Stephen, Avinash Alva, Punyawan Lumpaopong, Andy Williams and Andrew A. Amis

Finite element analysis of the pelvis including gait muscle forces: an investigation into the effect of rami fractures on load transmission

The objective of the study is to investigate the load transmission within the pelvic ring under physiological loading during gait and to correlate these results with clinical findings. In a second approach, we...

Authors: Pierre-Louis Ricci, Stefan Maas, Jens Kelm and Torsten Gerich

Contribution of sex and body constitution to three-dimensional lower extremity alignment for healthy, elderly, non-obese humans in a Japanese population

Humans support their bodies exclusively by vertical balance in bipedal locomotion, and the body, especially the lower extremity, generally changes with age. Sex and body constitution are assumed to be associat...

Authors: Ryota Katsumi, Tomoharu Mochizuki, Takashi Sato, Koichi Kobayashi, Satoshi Watanabe, Osamu Tanifuji and Naoto Endo

Effects of knee flexion and extension on the tibial tuberosity–trochlear groove (TT–TG) distance in adolescents

Measurement of the tibial tubercle–trochlear groove (TT–TG) distance is used to assess patellofemoral instability and rotation. Since patellofemoral instability and acute patellar dislocation are common among ...

Authors: Juha-Sampo Suomalainen, Gideon Regalado, Antti Joukainen, Tommi Kääriäinen, Mervi Könönen, Hannu Manninen, Petri Sipola and Hannu Kokki

What role does metal allergy sensitization play in total knee arthroplasty revision?

Clinicians are often faced with the decision whether to revise a painful total knee replacement in patients who have chronic vague pain with no apparent explanation. A sensitive metal testing assay called the ...

Authors: David R. Lionberger, Justin Samorajski, Charlie D. Wilson and Andreana Rivera

A novel test for assessment of anterolateral rotatory instability of the knee: the tibial internal rotation test (TIR test)

Rotational instability of the knee may persist after anterior cruciate ligament (ACL) reconstruction, which may be due to insufficiency of anterolateral stabilizing structures. However, no reliable diagnostic ...

Authors: Malou E. Slichter, Nienke Wolterbeek, K. Gie Auw Yang, Jacco A. C. Zijl and Tom M. Piscaer

Numerical comparative study of five currently used implants for high tibial osteotomy: realistic loading including muscle forces versus simplified experimental loading

Many different fixation devices are used to maintain the correction angle after medial open wedge high tibial osteotomy (MOWHTO). Each device must provide at least sufficient mechanical stability to avoid loss...

Authors: Arnaud Diffo Kaze, Stefan Maas, Slawomir Kedziora, James Belsey, Alexander Haupert, Claude Wolf, Alexander Hoffmann and Dietrich Pape

The spread of Injectate after ultrasound-guided lateral elbow injection – a cadaveric study

Injections into the tendinous portion of the common extensor origin are a common intervention in the treatment of Lateral Elbow Tendinopathy (LET). Clinical trials report a heterogeneous selection of injectate...

Authors: Jonathan P. Evans, Jeremy Metz, Rahul Anaspure, William J. Thomas, Andrew King, Vicki A. Goodwin and Chris D. Smith

Platelet-rich plasma does not reduce skeletal muscle fibrosis after distraction osteogenesis

Skeletal muscle fibrosis caused by an increase in collagen deposition often occurs after distraction osteogenesis. Although studies are available reporting the effects of platelet-rich plasma (PRP) on tissue h...

Authors: Ichiro Tonogai, Fumio Hayashi, Toshiyuki Iwame, Tomoya Takasago, Tetsuya Matsuura and Koichi Sairyo

Impact of five different medial patellofemoral ligament-reconstruction strategies and three different graft pre-tensioning states on the mean patellofemoral contact pressure: a biomechanical study on human cadaver knees

The medial patellofemoral ligament (MPFL) is the main stabiliser of the patella and thus mostly reconstructed in the surgical treatment of patellofemoral dislocation. The aims of this study were to gain a bett...

Authors: Daniel Dornacher, Sabine Lippacher, Manfred Nelitz, Heiko Reichel, Anita Ignatius, Lutz Dürselen and Andreas Martin Seitz

Nonoperative treatment of muscle injuries - recommendations from the GOTS expert meeting

Muscle injuries are some of the most common injuries in sports; they have a high recurrence rate and can result in the loss of ability to participate in training or competition. In clinical practice, a wide va...

Authors: T. Hotfiel, R. Seil, W. Bily, W. Bloch, A. Gokeler, R. M. Krifter, F. Mayer, P. Ueblacker, L. Weisskopf and M. Engelhardt

Perioperative platelet rich plasma (PRP) in total hip arthroplasty through the Hardinge approach: protocol to study the effectiveness for gluteus medius healing

Platelet-rich plasma (PRP) has been used to support tendon regeneration mainly in sports medicine. PRP is a concentrate of platelet-rich plasma proteins derived from whole blood by centrifugation to remove ery...

Authors: Anni Aavikko, J. Puhakka, J. Haapala, J. Kukkonen, K. Mäkelä and J. Kosola

A novel approach to enhance ACL injury prevention programs

Efficacy studies have demonstrated decreased anterior cruciate ligament (ACL) injury rates for athletes participating in injury prevention programs. Typically, ACL injury prevention programs entail a combinati...

Authors: Alli Gokeler, Romain Seil, Gino Kerkhoffs and Evert Verhagen

MMP-3 in the peripheral serum as a biomarker of knee osteoarthritis, 40 years after open total knee meniscectomy

To explore potential biomarkers in a meniscectomy-induced knee osteoarthritis model, at forty years after meniscectomy.

Authors: Ioannis Pengas, Suzanne Eldridge, Aggelos Assiotis, Michael McNicholas, Joao Espregueira Mendes and Lior Laver

The effect of residency training on arthroscopic knot tying and knot stability: which knot is best tied by Orthopaedic surgery residents?

The aim of this study is to evaluate which of three arthroscopic knots are most reliably taught to and executed by residents at varying levels of training.

Authors: Kevin J. Cronin, Jacob L. Cox, Timothy M. Hoggard, Scott T. Marberry, Brandon G. Santoni and Charles C. Nofsinger