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Table 3 Differences in biomechanical outcomes between the different conditions in the cadaveric study

From: An anatomically shaped medial meniscus prosthesis is able to partially restore the contact mechanics of the meniscectomized knee joint

Outcome

Force

Condition 1

Condition 2

Differencea

95% CI

P-value

Medial peak pressure (MPa)

500 N

Native

Meniscectomy

2.0

[0.5, 3.5]

 < 0.05

Meniscectomy

Prosthesis

-1.3

[-2.9, 0.2]

NSb

Native

Prosthesis

0.7

[-0.8, 2.2]

NS

1000 N

Native

Meniscectomy

3.1

[1.5, 4.6]

 < 0.001

Meniscectomy

Prosthesis

-1.7

[-3.3, -0.2]

 < 0.05

Native

Prosthesis

1.3

[-0.2, 2.9]

NS

Medial mean pressure (MPa)

500 N

Native

Meniscectomy

0.6

[0.3, 0.8]

 < 0.001

Meniscectomy

Prosthesis

-0.4

[-0.8, -0.1]

 < 0.05

Native

Prosthesis

0.2

[-0.1, 0.5]

NS

1000 N

Native

Meniscectomy

0.9

[0.6, 1.2]

 < 0.001

Meniscectomy

Prosthesis

-0.7

[-1.0, -0.4]

 < 0.001

Native

Prosthesis

0.3

[-0.0 0.5]

NS

Medial contact area (mm2)

500 N

Native

Meniscectomy

-247

[-361, -133]

 < 0.001

Meniscectomy

Prosthesis

39

[-75, 153]

NS

Native

Prosthesis

-208

[-322, -94]

 < 0.001

1000 N

Native

Meniscectomy

-278

[-392, -164]

 < 0.001

Meniscectomy

Prosthesis

76

[-38, 190]

NS

Native

Prosthesis

-202

[-316, -88]

 < 0.001

Load sharingc

(%)

500 N

Native

Prosthesis

-3

[-30, 25]

NS

1000 N

Native

Prosthesis

-8

[-35, 20]

NS

Lateral mean pressure (MPa)

500 N

Native

Meniscectomy

-0.0

[-0.1, 0.1]

NS

Meniscectomy

Prosthesis

0.0

[-0.1, 0.1]

NS

Native

Prosthesis

-0.0

[-0.1, 0.1]

NS

1000 N

Native

Meniscectomy

-0.1

[-0.2, 0.0]

NS

Meniscectomy

Prosthesis

0.0

[-0.0, 0.1]

NS

Native

Prosthesis

-0.0

[-0.1, 0.1]

NS

  1. a Mean difference between condition 1 and 2: A positive difference means an increase from condition 1 to condition 2
  2. b Not significant, meaning p > 0.05
  3. c Percentage of medial compartment load transferred through the meniscus