Fig. 1

(A, C) The severity of fibrous collagen deposition, or SFb, (green) measured from confocal photomicrographs of PS-stained, paraffin sections from the synovium of KOA patients is relative to (B, D) LH2b (red) immunolabeled content (E) measured as pixel area of LH2b signal over total tissue area of serial sections from those stained with PS. Scale bars = 100 µm; ns = not significant (F, G) COL1 and Pyd output measured by ELISA from homogenates of FSCs grouped by low (gray circles) or high (black circles) SFb, represented by gray or black circles, associate to histological SFb severity values