Fig. 7From: Fracture healing in a polytrauma rat model is influenced by mtDNA:cGAS complex mediated pro-inflammationGraphical illustration of the mechanism underlying the immunomodulation driven improved fracture healing mediated by RU.521 inhibition of the cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) synthase (cGAS)—stimulator of interferon genes (STING) signaling pathway in a polytrauma (PT)Back to article page