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Table 3 Sensitivity analysis excluding L4 and L5 vertebrae in the dowelplasty group

From: A novel device with pedicular anchorage provides better biomechanical properties than balloon kyphoplasty for the treatment of vertebral compression fractures

 

Dowelplasty (n=7)

Balloon kyphoplasty (n=11)

Mean difference

(95%CI)

p-value**

 

Mean ±SD

(95%CI)

Mean ±SD

(95%CI)

Fracture load

 Pre-treatment (N)

1847 ± 712

(850 –2700)

2256 ± 775

(1736 –2777)

-409

(-1180 –362)

0.319

 Post-treatment (N)

2380 ± 757

(1500 –3440)

2109 ± 612

(1698 –2520)

271

(-416 –958)

0.650

 Net change (N)

533 ± 650

(-210 –1750)

-147 ± 815

(-695 –400)

680

(-96 –1457)

0.113

p-value*

0.078

 

0.520

    

Fracture energy

 Pre-treatment (Nmm)

2440 ± 1429

(850 –4725)

3104 ± 1502

(2095 –4113)

-663

(-2175 –848)

0.277

 Post-treatment (Nmm)

4430 ± 1773

(1875 –6880)

3819 ± 1343

(2917 –4722)

611

(-946 –2167)

0.497

 Net change (Nmm)

1990 ± 1049

(375 –3700)

716 ± 1673

(-408 –1840)

1274

(-233 –2781)

0.085

p-value*

0.016

 

0.123

    

Stiffness

 Pre-treatment (N/mm)

1404 ± 474

(755 –2004)

1743 ± 631

(1319 –2166)

-338

(-930 –254)

0.285

 Post-treatment (N/mm)

1354 ± 289

(953 –1736)

1180 ± 332

(957 –1403)

174

(-150 –499)

0.285

 Net change (N/mm)

-50 ± 601

(-1051 –719)

-562 ± 604

(-968 – -156)

512

-106 –1130)

0.211

 p-value*

0.938

 

0.005

    
  1. Abbreviations: SD Standard deviation, CI Confidence interval
  2. *P-values comparing pre- versus post-treatment using paired wilcoxon signed rank tests
  3. **P-values comparing dowelplasty versus kyphoplasty using unpaired wilcoxon rank sum tests