Table 2 Characteristics of the included studies
From: The role of bone marrow stimulation in rotator cuff repair: a systematic review and meta-analysis
Author, year | Study | Sample size | Total | Gender(M/F) | Age, years | Bone marrow stimulation technique | Definition of retear | Clinical Outcomes | Bias grade | Follow-up | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BMS | Non-BMS | BMS | Non-BMS | BMS | Non-BMS | ||||||||
Leonardo Osti 2013 [22] | RCT | 28 | 29 | 57 | 16/12 | 14/15 | 61.2 (38-73) | 59.8 (34-71) | • Used an awl for microfractures • 2-4 mm deep, 3-4 mm apart | Homogeneous low-intensity or partial high-intensity area (MRI) | UCLA,CMS | High risk | 24 months |
Giuseppe Milano 2013 [21] | RCT | 35 | 38 | 73 | 22/13 | 19/19 | 60.6 ± 10.1 | 63.1 ± 9.2 | • Used an awl for microfractures • 5 mm deep, 1.5 mm wide, 4 mm apart | Sugaya type III, IV, or V (MRI) | Dash,CMS | Low risk | 24 months |
Miguel Angel Ruiz Ibán 2021 [8] | RCT | 36 | 33 | 69 | 14/22 | 18/15 | 60.1 ± 7.88 | 57.8 ± 10.7 | • Used NanoFx Instrument for microfractures • 9 mm deep, 1 mm wide, 3-5 mm apart | Sugaya type IV, or V (MRI) | CMS,BPI,EQ-5D-3L | High risk | 12 months |
P. Lapner 2021 [20] | RCT | 41 | 47 | 88 | 13/28 | 19/28 | 58.8 ± 8.8 | 59.5 ± 8.6 | • Used a Kirschner wire for microfractures • 5 mm deep, 2 mm wide, 1 cm apart | Tendons were not in conti-nuity with an evidence of tearing (Ultrasound) | ASES,CMS,WORC | High risk | 24 months |
Felipe Toro 2022 [23] | RCT | 62 | 61 | 123 | 29/33 | 35/26 | 58.9 ± 7.7 | 57.8 ± 9.2 | “• Used an awl for microfractures • 3-5 mm deep, 3 mm apart” | Sugaya type IV, or V (MRI) | ASES,CMS | Low risk | 12 months |
Noboru Taniguchi 2015 [26] | CO | 44 | 67 | 111 | 26/18 | 42/25 | 64.7 ± 1.4 | 64.3 ± 1.1 | • Used a metal bar for microfractures • 3 mm wide, 3-5 mm apart | Sugaya type IV, or V (MRI) | JOA,UCLA | 9 | 12 months |
Chris Hyunchul Jo 2013 [7] | CO | 57 | 67 | 124 | 25/32 | 33/34 | 58.89 ± 8.67 | 60.10 ± 7.94 | • Used a rasp for multiple channeling • 10 mm deep, 2.1 mm wide, 4-5 mm apart | Sugaya type IV, or V (MRI) | ASES,CMS,UCLA,DASH,SST,SPADI | 7 | 24 months |
Chul Kim 2020 [24] | CO | 56 | 42 | 98 | 26/30 | 23/19 | 64.6 ± 6.0 | 64.2 ± 5.5 | • Used a custom-made awl for microfractures • 10 mm deep, 2 mm wide, 5 mm apart | French Society of Arthroscopy stage 3 or 4 (MRI and CTA) | ASES,UCLA,VAS,SSV | 9 | 24 months |
Anil Pulatkan 2020 [25] | CO | 44 | 40 | 84 | 11/13 | 15/25 | 58.1 ± 9.7 | 59.2 ± 10.1 | • Used a custom-made awl for microfractures • 5 mm deep, 1.3 mm wide, 4-5 mm apart | Sugaya type IV, or V (MRI) | CMS,VAS | 7 | 24 months |