Debridement, antibiotics, and implant retention in non-oncological femoral megaprosthesis infections: minimum 5 year follow-up

Journal of Experimental Orthopaedics

Table 1 Patient Demographics, diagnosis, management and outcomes

Patient	Age/sex	Prosthesis	Indication	Time to infection (days)	Microorganism(s)	Antibiotic Choice	N^o of debridement	ASA	Outcome	Complications	Follow Up (months)
1	57 F	PFR	Osteolysis	12	Staph A Pseudomonas	Rifampicin & Ciprofloxacin	2	2	Clear		136
2	63 M	PFR	Fracture	34	CNS	Vancomycin & Gentamicin	1	2	Clear		98
3	82 F	PFR	Fracture	118	Enterococcus	Amoxicillin	1	3	Clear		70
4	47 M	PFR	Infection	38	Staph A Pseudomonas	Rifampicin & Ciprofloxacin	2	2	2-Stage - Clear	DVT & PE	84
5	59 M	PFR	Osteolysis	16	CNS	Linezolid	1	2	Clear		128
6	67 F	PFR	Infection	90	Staph A Strep	Flucloxacillin & Amoxicillin	1	3	2-Stage - Clear		99
7	69 F	DFR	Fracture	21	MRSA	Linezolid	1	2	Clear		64
8	74 F	DFR	Fracture	43	MRSA	Linezolid	1	3	2-Stage - Clear	Antibiotic Intolerance	114
9	59 M	DFR	Aseptic Loosening	68	Staph A Enterococcus	Amoxicillin & Flucloxacillin, Followed by Doxycycline	2	1	Clear		130
10	79 F	DFR	Aseptic Loosening	145	CNS	Rifampicin & Ciprofloxacin	1	3	Clear		66
11	76 M	DFR	Fracture	109	Staph A Enterococcus	Amoxicillin & Flucloxacillin	1	3	2-Stage - Clear		81
12	72 F	TFR	Infection	78	CNS Pseudomonas Strep	Rifampicin & Ciprofloxacin	3	2	1-Stage & ABx Suppression	Dislocation	Died 4 Years Later
13	68 M	TFR	Fracture	14	Staph A	Rifampicin & Ciprofloxacin	1	2	Clear		112
14	70 F	TFR	Aseptic Loosening & Fracture	37	CNS MRSA	Linezolid	1	2	Clear		129

PFR Proximal Femoral Replacement, DFR Distal Femoral Replacement, TFR Total Femoral Replacement, Staph A Staphylococcus Aureus, CNS Coagulase Negative Staphylococcus, MRSA Methicillin Resistant Staphylococcus Aureus, Strep Streptococcus, Abx Antibiotics, DVT Deep Vein Thrombosis, PE Pulmonary Embolism