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Table 1 Characteristics across study period

From: Tacrolimus as an adjunct to autologous minced muscle grafts for the repair of a volumetric muscle loss injury

  Sham VML VML + MMG VML + Tacrolimus VML + MMG + Tacrolimus
n= 1 2 4
Body mass (kg)
 Week 0 39.4 ± 0.0 41.9 ± 2.3 41.7 ± 0.8
 Week 4 48.6 ± 0.0 49.9 ± 3.1 46.5 ± 0.7
 Week 8 54.2 ± 0.0 56.6 ± 2.8 51.8 ± 2.8
 Week 12 61.2 ± 0.0 65.3 ± 3.9 55.7 ± 3.3
Tacrolimus concentration (ng/ml)
 Day 3 nd nd 1.12 ± 0.29
 Day 9 nd nd 1.35 ± 0.14
 Week 2 nd nd 1.73 ± 0.25
 Week 3 nd nd 2.26 ± 0.65
 Week 4 nd nd 3.25 ± 1.58
 Week 6 nd nd nd
  1. Circulating levels of tacrolimus were analyzed; levels were non-detectible (nd) in the untreated and sham animals and 2 weeks following termination of treatment
  2. Mean ± standard error
  3. VML volumetric muscle loss, MMG minced muscle graft