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Table 1 Overview of Analyzed Gait Parameters

From: Measurement of mechanical withdrawal thresholds and gait analysis using the CatWalk method in a nucleus pulposus-applied rodent model

Parameters Explanation
Basic Average speed (cm/s) Speed of the animal’s body in the recorded run
Number of steps Total number of selected steps in one run
Body speed (cm/s) Speed calculated by dividing the distance that the animal’s body traveled from one initial contact of one paw to the next by the time to travel that distance
Body speed validation (%) Percentage calculated by dividing the absolute difference between the body speed and the average speed of a run by the average speed
Calculated from walking durations Stand (s) Duration of contact of a paw with the glass plate (Fig. 1)
Swing (s) Duration of no contact of a paw with the glass plate (Fig. 1)
Step cycle (s) Time in seconds between two consecutive initial contacts of the same paw: stand + swing (Fig. 1)
Duty cycle (%) Stand as a percentage of step cycle: stand / (stand + swing) × 100 (Fig. 1)
Calculated from bilateral paw durations Initial dual stance (s) The duration of ground contact for both hind paws simultaneously, but the first one in a step cycle of a target hind paw (Fig. 1)
Terminal dual stance (s) The duration of ground contact for both hind paws simultaneously, but the latter one in a step cycle of a target hind paw (Fig. 1)
Single stance (s) Duration in seconds of ground contact for a single hind paw
Calculated from the data of maximum contact Stand index Speed at which the paw loses contact with the glass plate
Max contact at (%) Max contact at (s) relative to stand of a paw Max contact at (s): the time in seconds since the start of the run that a paw makes maximum contact with the glass plate
Max contact area (cm2) Maximum area of a paw that comes into contact with the glass plate
Calculated from the light intensity data Max contact max intensity Maximum intensity at maximum contact of a paw
Max contact mean intensity Mean intensity of a paw at maximum contact
Max intensity at (%) Max intensity at (s) relative to stand of a paw Max intensity at (s): time in seconds since the start of the run that the maximum intensity is measured
Max intensity Maximum intensity of the complete paw
Min intensity Minimum intensity of the complete paw
Mean intensity Mean intensity of the complete paw
Calculated from the data of the complete paw print Print length (cm) Length (horizontal direction) of the complete print
Print width (cm) Width (vertical direction) of the complete paw print
Print area (cm2) Surface area of the complete print
Swing speed (cm/s) Speed of the paw during swing: stride length / swing
Stride length (cm) Distance between successive placements of the same paw
Other Regularity index (%) Number of normal step sequence patterns relative to the total number of paw placements
Base of support (cm) Average width between either the front paws or the hind paws (base of support of hind paws was analyzed in this study)
Sciatic functional index Measure of the functional recovery of the sciatic nerve that innervates the hind paws
Phase dispersions Parameters describing the temporal relationship between placement of two paws within a step cycle: ((Initial contact of target paw – Initial contact of anchor paw) / step cycle of anchor paw) × 100 (Fig. 1) Phase dispersions of two girdle pairs (right forepaw and left forepaw: LF-RF, right hind paw and left hind paw: LH-RH) were analyzed Left paws were always set as the anchor paw