Journal of Experimental Orthopaedics

Table 2 Results of urine calcium, Dpd, and creatinin values after BMX

From: The biochemical and histological analysis of subcutaneous calcitonin and intramedullary methylprednisolone on bone repair after bone marrow ablation: an experimental comparative study in rats

		Days after BMX					p (ANOVA)
	Day 0 (n = 8)	1 (n = 8)	3 (n = 8)	7 (n = 8)	9 (n = 8)	15 (n = 4)	p (ANOVA)
Urine Calcium level (mg/dl/24 h)
Control group	6.42 ± 1.73	6.91 ± 1.57	15.61 ± 2.97 ^ce†	23.74 ± 7.91 ^‡	8.74 ± 2.91	9.45 ± 2.78	< .0001
Calcitonin group	6.42 ± 1.73	6.84 ± 2.44	6.27 ± 1.82	9.14 ± 3.28 ^ae	8.40 ± 2.14	7.85 ± 1.92	NS
Steroid group	6.42 ± 1.73	6.81 ± 3.58	6.83 ± 3.56	20.08 ± 7.14 ^†	31.47 ± 6.35 ^bd‡	19.41 ± 8.42^†	< .0001
Urine Dpd level (μg/day)
Control group	126.4 ± 28.6	69.2 ± 16.4	117.0 ± 36.5 ^f	159.6 ± 42.6 ^cf	227.3 ± 84.4 ^df†	72.4 ± 16.8	.0026
Calcitonin group	126.4 ± 28.6	51.8 ± 13.3	107.6 ± 16.8 ^e	89.4 ± 24.3 ^f	91.5 ± 17.9	138.7 ± 14.6 ^be	.0081
Steroid group	126.4 ± 28.6	48.9 ± 9.4	72.9 ± 7.6	32.9 ± 13.5 ^‡	72.4 ± 26.4	92.5 ± 22.8	.0013
Urine Cr eatinin level (mg/day)
Control group	122.3 ± 12.5	139.3 ± 44.5	102.9 ± 38.4 ^e	82.3 ± 31.5 ^e	80.0 ± 45.3	82.6 ± 56.5	.017
Calcitonin group	122.3 ± 12.5	143.0 ± 44.1	131.2 ± 55.3	118.2 ± 34.1	132.6 ± 70.8	102.5 ± 27.3	NS
Steroid group	122.3 ± 12.5	141.8 ± 27.9	175.8 ± 45.8	175.1 ± 88.8	94.2 ± 38.4	99.5 ± 22.1	.005

All values are expressed as mean ± S.D. Dpd: deoxypyridinoline
^a p < 0.05, ^b p < 0.01,significantly different from control group
^c p < 0.05, ^d p < 0.01, significantly different from calcitonin group
^e p < 0.05, ^f p < 0.01, significantly different from steroid group
^† p < 0.05, ^‡ p < 0.01 significantly different from day 0

Back to article page