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Table 6 Percent of OMERACT-OARSI responders in different patient populations

From: White blood cell concentration correlates with increased concentrations of IL-1ra and improvement in WOMAC pain scores in an open-label safety study of autologous protein solution

% Responders

Week 1

Week 2

Week 4

Month 3

Month 6

Total Population

20.0

45.5

63.6

72.7

72.7

IL-1ra:IL-1β Ratio > 1000

28.6

71.4

71.4

100.0

85.7

WBC > 30 k/μl

28.6

71.4

71.4

100.0

85.7

  1. *Total population (n = 11), patients with APS whose IL-1ra:IL-1β ratio > 1000 (n = 7/9), and with WBC concentration in APS > 30 k/μl (n = 7/8)