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Table 3 Average concentrations of cytokines in whole blood and APS. (average ± standard deviation, n = 9)

From: White blood cell concentration correlates with increased concentrations of IL-1ra and improvement in WOMAC pain scores in an open-label safety study of autologous protein solution

Metric IL-1ra sIL-1RII IL-1β sTNF-RII TNFα
Whole Blood Concentration (pg/ml) 8,029 ± 2,818 6,798 ± 1,623 1.6 ± 0.9 1,036 ± 188 0.7 ± 1.2
APS Concentration (pg/ml) 57,511 ± 24,272 20,121 ± 6,654 20.3 ± 34.2 5,520 ± 1,174 2.6 ± 2.9
Blood Concentration Range (pg/ml) 3,450–11,750 4,622–9,050 0.7–3.3 891–1,563 0.0–3.4
APS Concentration Range (pg/ml) 23,100–97,750 11,350–28,155 2.8–109.3 3,934–7,556 0–7.5
p values 6.8E–05 2.0E–05 0.07 6.2E–07 0.02