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Table 6 Mean Modified O’Driscoll score for each category

From: Osteochondral tissue engineering using a biphasic collagen/GAG scaffold containing rhFGF18 or BMP-7 in an ovine model

   Empty defect Scaffold only rhFGF18 BMP-7
   MFC LTS MFC LTS MFC LTS MFC LTS
I % Hyaline Cartilage: 0.80 1.00 1.00 1.67 3.00 2.00 1.33 0.00
II Structural Characteristics:         
  A. Surface Irregularity: 0.20 0.75 1.17 1.83 1.83 1.33 0.67 0.83
  B. Structural integrity: 0.40 0.50 0.67 1.00 1.17 0.50 0.83 0.50
  C. Thickness: 0.80 0.75 0.83 0.83 1.33 0.67 1.00 0.33
  D. Bonding to adjacent cartilage: 1.20 1.00 2.00 1.50 1.83 1.67 2.00 1.17
III Freedom from cellular changes of degeneration: 0.60 0.25 0.67 1.00 0.83 0.83 1.00 0.50
IV Freedom from degenerate changes in adjacent cartilage: 1.80 1.75 2.17 1.50 2.33 2.33 2.50 2.33
V Reconstitution of subchondral bone: 1.00 0.75 0.33 0.67 0.67 0.83 1.17 0.50
VI Bonding of repair cartilage to denovo subchondral bone: 1.60 1.00 1.33 1.67 1.83 1.67 2.00 1.33
VII Safranin O: 0.60 0.50 1.00 1.00 2.00 1.33 1.50 0.33
  MEAN TOTAL SCORE 9.00 8.25 11.17 12.70 16.83 13.20 14.00 7.83
  p < 0.05 *     *    
  1. * indicates significant differences between specific groups p = 0.039. All other group comparisons p > 0.05.