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Table 6 Mean Modified O’Driscoll score for each category

From: Osteochondral tissue engineering using a biphasic collagen/GAG scaffold containing rhFGF18 or BMP-7 in an ovine model

  

Empty defect

Scaffold only

rhFGF18

BMP-7

  

MFC

LTS

MFC

LTS

MFC

LTS

MFC

LTS

I

% Hyaline Cartilage:

0.80

1.00

1.00

1.67

3.00

2.00

1.33

0.00

II

Structural Characteristics:

        
 

A. Surface Irregularity:

0.20

0.75

1.17

1.83

1.83

1.33

0.67

0.83

 

B. Structural integrity:

0.40

0.50

0.67

1.00

1.17

0.50

0.83

0.50

 

C. Thickness:

0.80

0.75

0.83

0.83

1.33

0.67

1.00

0.33

 

D. Bonding to adjacent cartilage:

1.20

1.00

2.00

1.50

1.83

1.67

2.00

1.17

III

Freedom from cellular changes of degeneration:

0.60

0.25

0.67

1.00

0.83

0.83

1.00

0.50

IV

Freedom from degenerate changes in adjacent cartilage:

1.80

1.75

2.17

1.50

2.33

2.33

2.50

2.33

V

Reconstitution of subchondral bone:

1.00

0.75

0.33

0.67

0.67

0.83

1.17

0.50

VI

Bonding of repair cartilage to denovo subchondral bone:

1.60

1.00

1.33

1.67

1.83

1.67

2.00

1.33

VII

Safranin O:

0.60

0.50

1.00

1.00

2.00

1.33

1.50

0.33

 

MEAN TOTAL SCORE

9.00

8.25

11.17

12.70

16.83

13.20

14.00

7.83

 

p < 0.05

*

   

*

   
  1. * indicates significant differences between specific groups p = 0.039. All other group comparisons p > 0.05.