Table 1 Mesenchymal stem cells for meniscus regeneration

• High regenerative potential

• High treatment costs

• Self renewal capacity

• Regulatory burden

• Cellular modulation at lesion site

• Missing knowledge of underlying repair mechanisms

• Potential of differentiation into meniscal repair cells

• Possible need for cell expansions prior to application

• Secretion of bioactive substances like growth factors

• Support/promotion of intrinsic meniscal healing capacity