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Table 1 Advantages, disadvantages, and the optimal patient for different ACL graft options

From: Current trends in graft choice for primary anterior cruciate ligament reconstruction – part II: In-vivo kinematics, patient reported outcomes, re-rupture rates, strength recovery, return to sports and complications

Graft Type

Optimal Patient

Advantages

Disadvantages

QT

 < 35 years old

High-level pivoting sport and/or

high physical demand

Work, activity or sport that requires kneeling

Skeletally immature patients

Comparable graft rupture rates to BPTB

Lower donor site morbidity than BPTB but comparable to HT

Possibility of single side bone-block harvest

Possibility of individualized graft size by harvesting partial- or full thickness graft

Less flexion strength loss compared to HT

No long-term outcomes

Decreased extensor strength

Risk of patellar fracture or quadriceps tendon rupture

BPTB

 < 35 years old

High-level pivoting sports

high physical demand

Bone-to-bone healing and therefore possibly more aggressive rehabilitation

Low graft rupture rates comparable to QT

High return to sport rates

Highest rate of donor site morbidity and anterior knee pain

Higher rates of OA progression

Risk of patellar fracture or patella tendon rupture

No option for skeletally immature patients

Possible higher risk of contralateral ACL rupture

Decreased extensor strength

HT

Moderate sport and/or activity level

Small ACL footprint

Work, activity or sport that requires kneeling

Skeletally immature patients

Lower donor site morbidity compared to BPTB

Possibility of individualized graft size by additional gracilis tendon harvest and different graft configurations

No risk for patellar fracture or extensor mechanism rupture

Lower OA progression than BPTB

Higher graft rupture rates compared to QT and BPTB, especially in young and active patients

Increased ATT after HT ACL-R, possibly due to reduction in hamstring force

Tendency towards higher surgical site infection rates

Decreased flexion strength

Allograft

 > 40 years old

Low activity level and/or physicaldemand

Multiligament Knee Injury

No donor site morbidity

Faster operation time

More predictable graft size

Higher graft rupture rates compared to QT and BPTB, especially in young and active patients

Slower rehabilitation speed due to delayed graft maturation and incorporation

Increased costs

  1. QT Quadriceps Tendon Autograft, BPTB Bone-Patellar-Tendon-Bone Autograft, HT Hamstring Tendon Autograft, ACL-R Anterior Cruciate Ligament Reconstruction, ATT Anterior Tibial Translation, OA Osteoarthritis