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Table 12 Associations between patient factors and an unsatisfactory outcome after SVF implantation

From: Cartilage lesion size and number of stromal vascular fraction (SVF) cells strongly influenced the SVF implantation outcomes in patients with knee osteoarthritis

Factors

n (%)

Unsatisfactory outcome,

odds ratio (95% CI)

P value

Age, y

  

n.s

  < 60

4 (9.3)

1.50 (0.06–40.63)

 

 60–65

24 (55.8)

1.21 (0.09–145.66)

 

 65–70

12 (27.9)

0.25 (0.02–3.67)

 

  ≥ 70

3 (7.0)

1.00

 

Sex

  

n.s

 Male

14 (32.6)

1.00

 

 Female

29 (67.4)

1.23 (0.34–4.49)

 

Involved side

  

n.s

 Right

21 (48.8)

1.67 (0.48–5.74)

 

 Left

22 (51.2)

1.00

 

Body mass index, kg/m2

  

n.s

  < 20.0

2 (4.7)

1.00

 

 20.0–24.9

15 (34.8)

1.34 (0.08–12.83)

 

 25.0–29.9

24 (55.8)

2.29 (0.17–30.96)

 

  ≥ 30.0

2 (4.7)

3.75 (0.29–47.99)

 

Lesion location

  

n.s

 Medial femoral condyle

41 (65.1)

1.00

 

 Lateral femoral condyle

16 (25.4)

1.41 (0.25–7.86)

 

 Trochlea

6 (9.5)

2.20 (0.32–14.98)

 

Lesion size, cm2

  

0.038

  < 3.5

4 (9.3)

1.00

 

 3.5–5.5

18 (41.9)

2.67 (0.23–31.07)

 

 5.5–7.5

17 (39.5)

7.80 (0.65–93.81)

 

  ≥ 7.5

4 (9.3)

13.4 (2.49–215.36)

 

No. of SVF cells

  

0.021

  < 7.0 × 107

12 (27.9)

7.20 (0.64–81.54)

 

 7.0 × 107–8.0 × 107

25 (58.1)

1.80 (0.43–7.53)

 

  ≥ 8.0 × 107

6 (14.0)

1.00

 
  1. SVF Stromal vascular fraction, CI Confidence interval