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Table 2 Opioid Prescriptions During First 3 Months After TKA

From: A modern multimodal pain protocol eliminates the need for opioids for most patients following total knee arthroplasty: results from a retrospective comparative cohort study

Outcomea

Automatic

(n = 72)

Upon Request

(n = 72)

P value

All Patients

  ≥ 1 filled opioid prescription, % (n)

95.8 (69)

44.4 (32)

< 0.0001

 No. of prescriptions

1 (0–8)

0 (0–8)

< 0.0001

  ≥ 1 refill, % (n)

43.1 (31)

25.0 (18)

0.022

Patients with ≥1 Opioid Prescription

 No. of prescriptions

1 (1–8)

2 (1–8)

0.111

 Patients with ≥1 Opioid Refill

No. of refills

2 (1–7)

3 (1–6)

0.093

 Opioid-naïve Patients, n

56

50

 

  ≥ 1 filled opioid prescription, % (n)

94.6 (53)

28.0 (14)

< 0.0001

 No. of prescriptions

1 (0–8)

0 (0–7)

< 0.0001

  ≥ 1 refill, % (n)

33.9 (19)

10.0 (5)

0.003

Opioid-naïve patients with ≥1 Opioid Prescription

 No. of prescriptions

1 (1–8)

1 (1–7)

0.704

Opioid-naïve patients with ≥1 Opioid Refill

 No. of refills

3 (1–6)

3 (1–7)

0.823

 Opioid-experienced Patients, n

16

22

 

  ≥ 1 filled opioid prescription, % (n)

100 (16)

81.8 (18)

0.124

 No. of prescriptions

3 (1–7)

2 (0–8)

0.352

  ≥ 1 refill, % (n)

75.0 (12)

59.1 (13)

0.490

Opioid- experienced patients with ≥1 Opioid Prescription

 No. of prescriptions

3 (1–7)

2.5 (1–8)

1.000

  1. aAll values are median (range) unless otherwise specified
  2. MME Morphine milligram equivalent, TKA Total knee arthroplasty