Parameters | Week | TII collagen (N = 32) | G + C (N = 31) | Placebo (N = 31) | p-value | ||
---|---|---|---|---|---|---|---|
Overall | TII collagen vs placebo | G + C vs placebo | |||||
WOMAC- total score | 4 | -15.28 ± 13.76 | -17.94 ± 16.52 | -5.87 ± 12.61 | 0.0036 | 0.0099 | 0.0015 |
8 | -22.75 ± 15.30 | -25.19 ± 20.06 | -10.52 ± 13.42 | 0.0012 | 0.0030 | 0.0007 | |
12 | -32.47 ± 19.51 | -33.74 ± 24.64 | -13.84 ± 17.61 | 0.0002 | 0.0003 | 0.0003 | |
WOMAC- pain score | 4 | -2.25 ± 3.01 | -2.94 ± 3.35 | -1.10 ± 2.75 | - | - | 0.0239 |
8 | -3.94 ± 2.61 | -4.26 ± 3.95 | -1.87 ± 2.95 | 0.0053 | 0.0049 | 0.0048 | |
12 | -5.69 ± 3.66 | -6.03 ± 4.72 | -2.71 ± 3.95 | 0.0023 | 0.0024 | 0.0024 | |
WOMAC- stiffness score | 4 | -1.00 ± 1.52 | -1.42 ± 1.46 | -0.23 ± 1.09 | 0.0030 | 0.0093 | 0.0013 |
8 | -1.53 ± 1.70 | -1.97 ± 1.62 | -0.61 ± 1.38 | 0.0014 | 0.0024 | 0.0012 | |
12 | -2.19 ± 1.75 | -2.71 ± 2.05 | -0.84 ± 1.27 | < 0.0001 | 0.0002 | < 0.0001 | |
WOMAC- physical function score | 4 | -12.03 ± 10.16 | -13.58 ± 12.53 | -4.55 ± 9.35 | 0.0028 | 0.0068 | 0.0014 |
8 | -17.28 ± 12.00 | -18.97 ± 15.62 | -8.03 ± 10.19 | 0.0017 | 0.0042 | 0.0010 | |
12 | -24.59 ± 15.00 | -25.00 ± 18.90 | -10.29 ± 13.07 | 0.0002 | 0.0003 | 0.0002 |