Table 1 Main inclusion and exclusion criteria for the study
Criteria | Basic conditions |
|---|---|
Inclusion criteria | 1. Age ≥ 40 to ≤ 65 years |
2. BMI ≥ 18.5 and ≤ 29.9 kg/m2 | |
3. Non-vegetarians | |
4. VAS score ≥ 60 mm for knee joint pain | |
5. Willing to abstain from food containing Type II collagen from cartilage 48 h before all assessment visits | |
Exclusion criteria | 1. FBG > 125 mg/dL |
2. SBP ≥ 140 mmHg and/or DBP ≥ 90 mmHg | |
3. Radiographic evidence of Grade I or Grade IV OA based on the Kellgren and Lawrence criteria for osteoarthritis | |
4. Any history of trauma, fractures, or surgery to the index joint 5. History of use of corticosteroids (oral or parenteral) and hyaluronic acid (intra-articular) for the last three days | |
6. Usage of local and/or systemic analgesics |