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Fig. 8 | Journal of Experimental Orthopaedics

Fig. 8

From: Systematic review on the application of 3D-bioprinting technology in orthoregeneration: current achievements and open challenges

Fig. 8

Functional evaluation of prevascularized spheroid-laden bioprinted scaffolds by a CAM-assay

a Overview of bioprinted sample on the CAM, scale bar = 5 mm. b Macroscopic and stereomicroscopic images of empty scaffolds and spheroid-laden scaffolds on the CAM. Overview scale bars = 5 mm and magnification scale bars = 500 µm. c Details of spheroid-laden scaffolds on the CAM. Branching of CAM microvessels and inosculation of CAM microvasculature with the spheroids (indicated by the black arrows). Scale bars = 200 µm. Reprinted with permission from Biofabrication [49]

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