Comparison of weekly and single dose intraarticular recombinant human growth hormone injection on cartilage degeneration in osteoarthritic model of white New Zealand rabbits

Journal of Experimental Orthopaedics

Table 4 Statistical analysis and comparison of Mankin score between groups

Mankin Microscopic Score	Mean Difference	CI 95%		P value
Mankin Microscopic Score	Mean Difference	Min	Max	P value
Control *vs.* GH1 group	3.17	1.06	5.27	0.004*
Control *vs.* GH3 group	4.17	2.32	6.01	< 0.001*
Control *vs.* GH5 group	5.50	3.65	7.34	< 0.001*
GH1 *vs.* GH3	1.00	- 0.79	2.79	0.352
GH1 *vs.* GH5	2.33	0.54	4.12	0.013*
GH3 *vs.* GH5	1.33	0.003	2.66	0.049*

*p<0.005; Post hoc Games−Howell test; GH1 single dose growth hormone injection, GH3 3 times weekly dose growth hormone injection, GH5 5 times weekly dose growth hormone injection, Control: placebo