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Table 2 Relative counts of T cells in the fracture site at 1 week post-trauma (wpt) in osteotomy rats (OST), polytrauma rats (PT-C), PT rats with chicken IgY isotype (PT-IgY), and PT rats with anti-HMGB1 (PT-Ab HMGB1) rats. OST (n = 5), PT-C (n = 5), PT-IgY (n = 4) and PT-Ab HMGB1 (n = 8) rats, respectively. * p < 0.05 for OST vs PT-IgY and PT-C and ** p < 0.05 for PT-Ab HMGB1 vs PT-IgY and PT-C

From: Neutralization of HMGB1 improves fracture healing and γδ T lymphocyte counts at the fracture site in a polytrauma rat model

T cells

Cell counts (Mean ± SD)

 

OST

PT-C

PT-IgY

PT-Ab HMGB1

CD3+ T cells

2233 ± 855

2052 ± 877

2072 ± 339

2038 ± 536

CD3+ CD4+ T cells

1632 ± 650

1446 ± 580

1393 ± 338

1458 ± 418

CD3+ CD8+ T cells

344 ± 154

331 ± 224

334 ± 117

301 ± 232

CD3+ CD4+ CD8+ T cells

156 ± 82

208 ± 104

370 ± 77

173 ± 92

CD3+ γδTCR+ T cells

237 ± 104*

105 ± 36

96 ± 33

234 ± 57* *