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Journal of Experimental Orthopaedics
Fig. 6 | Journal of Experimental Orthopaedics

Fig. 6

From: A novel mice model of acute flares in osteoarthritis elicited by intra-articular injection of cultured mast cells

Fig. 6

A Effect of Tranilast on articular cartilage degeneration and MC infiltration in the synovium around the meniscosynovial junction. Arrowhead indicated MC. B Modified Mankin score (Median [interquartile range]). C Number of MC located in the synovium around the meniscosynovial junction. (Median [interquartile range]). T ( +) group (n = 13), T (-) group (n = 13). *: P < 0.05 compared with T (-) group (white bar: 50 μm). D Levels of mRNA expression ratio (T ( +) divided by T (-)) of IL-1β, TNF-α, IL-6, ADAMTS-4, and NGF. Each plotted circle contains an infrapatellar fat pads from three mice (bar: median *: P < 0.05 compared with T (-) group)

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