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Table 3 Comparison of preoperative and postoperative clinical outcomes according to the presence of radiological worsening in both groups

From: Comparative matched-pair cohort analysis of the short-term clinical outcomes of mesenchymal stem cells versus hyaluronic acid treatments through intra-articular injections for knee osteoarthritis

 

MSC

HA

Radiological worsening

Radiological worsening

Presence (n = 2)

Absence (n = 28)

P valuea

Presence (n = 6)

Absence (n = 24)

P valuea

VAS

 Baseline

8.0 ± 1.4

8.4 ± 1.1

0.604

8.5 ± 1.0

8.0 ± 1.1

0.359

 1 year

5.5 ± 2.1

4.8 ± 1.1

0.372

5.7 ± 1.0

5.3 ± 1.0

0.404

 P valueb

<  0.001

<  0.001

 

<  0.001

<  0.001

 

IKDC score

 Baseline

42.0 ± 11.3

36.7 ± 7.7

0.366

35.5 ± 4.6

40.1 ± 6.4

0.110

 1 year

68.0 ± 8.5

65.9 ± 5.1

0.588

60.3 ± 6.1

62.5 ± 7.2

0.512

 P valueb

<  0.001

<  0.001

 

<  0.001

<  0.001

 

Lysholm score

 Baseline

57.5 ± 10.6

54.2 ± 6.2

0.489

51.7 ± 4.2

56.0 ± 7.8

0.095

 1 year

78.0 ± 11.3

77.6 ± 6.1

0.927

70.8 ± 5.8

74.6 ± 5.7

0.160

 P valueb

<  0.001

<  0.001

 

<  0.001

<  0.001

 
  1. Data are expressed as mean ± standard deviation. MSC Mesenchymal stem cell, HA Hyaluronic acid, VAS Visual analog scale, IKDC International Knee Documentation Committee
  2. aMann–Whitney U test
  3. bWilcoxon signed-rank test for comparison of clinical outcomes at baseline versus I year after the injection