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Table 2 Patient demographics from the included studies

From: Sporting participation following the operative management of chondral defects of the knee at mid-term follow up: a systematic review and meta-analysis

 

MFX

ACI

MACI

OAT

Allograft

PRP + PBSC

Overall

Studies

5

6

7

8

4

1

29a

Patients (n)

201

240

347

271

197

20

1276

Age in years (SD)

32.0 (± 4.5)

33.1 (± 4.3)

34.9 (± 4.8)

32.6 (± 8.5)

29.5 (± 3.6)

32.7(± 7.5)

32.8 (± 5.7)

Gender (M/F, %)

69/31

68/32

67/33

73/27

58/42

65/35

67/33

BMI

NR

24.3 (± 0.5)

26.1 (± 0.8)

25.0 (± 2.5)

25.0 (± 0.6)

26.0 (± 2.7)

25.3 (± 1.0)

Follow up in months (SD)

114.1 (± 51.8)

71.8 (± 15.9)

65.5 (± 17.1)

136.5 (± 47.9)

71.9 (± 0.3)

61.2 (NR)

88.8 (± 42.4)

Preoperative duration of symptoms in months (SD)

NR

32.9 (± 5.1)

94.6 (± 15.3)

NR

58.4 (± 1.0)

4.3 (NR)

71.9 (± 28.1)

Preoperative mean Tegner score (SD)

3.2 (NR)

3.50 (± 1.3)

1.9 (± 0.5)

2.9 (± 0.0)

NR

NR

2.5 (± 0.7)

Preoperative mean Lysholm score (SD)

50.7 (± 5.7)

40.5 (± 0.4)

53.8 (± 6.9)

64.7 (± 5.2)

41.0 (± 13.0)

NR

52.7 (± 9.3)

Preoperative mean IKDC subjective score (SD)

44.5 (± 2.8)

41.3 (1.4)

40.3 (± 13.4)

34.8 (± 13.5)

38.0 (± 12.0)

50.5 (± 6.3)

42.1 (± 4.0)

Chondral defects

 Size in cm2 (SD)

3.5 (± 0.7)

4.0 (± 1.4)

3.6 (± 1.2)

2.4 (± 0.5)

4.5 (± 1.8)

NR

3.4 (± 1.2)

 MFC (n)

99

120

187

155

9

NR

570

 LFC (n)

37

37

74

54

6

NR

217

 Trochlea (n)

13

18

14

16

21

9

90

 Patella (n)

7

68

11

4

12

6

108

  1. NR not reported; MFX microfracture, ACI autologous chondrocyte implantation, MACI matrix-induced autologous chondrocyte implantation, OAT osteochondral autograft transfer, PRP platelet-rich plasma, PBSC peripheral blood stem cells, M male, F female, IKDC international knee documentation committee, MFC medial femoral condyle, LFC lateral femoral condyle. aTwo studies compared more than one biologic technique