| MFX | ACI | MACI | OAT | Allograft | PRP + PBSC | Overall |
---|---|---|---|---|---|---|---|
Studies | 5 | 6 | 7 | 8 | 4 | 1 | 29a |
Patients (n) | 201 | 240 | 347 | 271 | 197 | 20 | 1276 |
Age in years (SD) | 32.0 (± 4.5) | 33.1 (± 4.3) | 34.9 (± 4.8) | 32.6 (± 8.5) | 29.5 (± 3.6) | 32.7(± 7.5) | 32.8 (± 5.7) |
Gender (M/F, %) | 69/31 | 68/32 | 67/33 | 73/27 | 58/42 | 65/35 | 67/33 |
BMI | NR | 24.3 (± 0.5) | 26.1 (± 0.8) | 25.0 (± 2.5) | 25.0 (± 0.6) | 26.0 (± 2.7) | 25.3 (± 1.0) |
Follow up in months (SD) | 114.1 (± 51.8) | 71.8 (± 15.9) | 65.5 (± 17.1) | 136.5 (± 47.9) | 71.9 (± 0.3) | 61.2 (NR) | 88.8 (± 42.4) |
Preoperative duration of symptoms in months (SD) | NR | 32.9 (± 5.1) | 94.6 (± 15.3) | NR | 58.4 (± 1.0) | 4.3 (NR) | 71.9 (± 28.1) |
Preoperative mean Tegner score (SD) | 3.2 (NR) | 3.50 (± 1.3) | 1.9 (± 0.5) | 2.9 (± 0.0) | NR | NR | 2.5 (± 0.7) |
Preoperative mean Lysholm score (SD) | 50.7 (± 5.7) | 40.5 (± 0.4) | 53.8 (± 6.9) | 64.7 (± 5.2) | 41.0 (± 13.0) | NR | 52.7 (± 9.3) |
Preoperative mean IKDC subjective score (SD) | 44.5 (± 2.8) | 41.3 (1.4) | 40.3 (± 13.4) | 34.8 (± 13.5) | 38.0 (± 12.0) | 50.5 (± 6.3) | 42.1 (± 4.0) |
Chondral defects | |||||||
 Size in cm2 (SD) | 3.5 (± 0.7) | 4.0 (± 1.4) | 3.6 (± 1.2) | 2.4 (± 0.5) | 4.5 (± 1.8) | NR | 3.4 (± 1.2) |
 MFC (n) | 99 | 120 | 187 | 155 | 9 | NR | 570 |
 LFC (n) | 37 | 37 | 74 | 54 | 6 | NR | 217 |
 Trochlea (n) | 13 | 18 | 14 | 16 | 21 | 9 | 90 |
 Patella (n) | 7 | 68 | 11 | 4 | 12 | 6 | 108 |