Table 2 Indications and contraindications for scaffold-based meniscal substitutes and meniscal allograft transplantation
From: Meniscal substitution, a developing and long-awaited demand
| Â | Scaffold-based meniscal substitution | Meniscal allograft transplantation |
|---|---|---|
Indications | Clinical symptoms s/p extensive partial meniscal resection Stable meniscal rim Intact meniscal roots Chronic partial meniscal defect | Clinical symptoms s/p sub−/total meniscal resection Insufficient meniscal rim Insufficient meniscal roots |
Contraindications | Age: >  50 yearsa BMI: >  35a Insufficient meniscal rim Insufficient meniscal roots Knee instability Limb malalignment Allergies to animal derived products Meniscal defect limited to zone 3 (Fig. 1) ICRS grade > 3 Active infection Autoimmune diseases Inflammatory arthritis Smokera | Age: >  50 yearsa BMI: >  35a Outerbridge grade III, IV Fairbank grade > 2 Joint space narrowing Knee instability Limb malalignment Active infection Autoimmune diseases Inflammatory arthritis Smokera |