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Fig. 5 | Journal of Experimental Orthopaedics

Fig. 5

From: RETRACTED ARTICLE: Titanium particles damage osteocytes and inhibit osteoblast differentiation

Fig. 5

Sclerostin protein expression of MLO-Y4 cells treated with Ti particles (0 (control), 0.1 mg/mL, or 1.0 mg/mL) for 24 h and 48 h. Levels of sclerostin protein were detected by Western blot, and GAPDH was used as an endogenous control. b The quantitative datafor sclerostin levels is expressed as band-density ratios compared to the control group at 24 h. Sclerostin expression was significantly higher in the 1.0 mg/mL group than the control group or the 0.1 mg/mL group (*p < 0.05). c The quantitative data for sclerostin levels is expressed as band-density ratios compared to the control group at 48 h. Treatment with 0.1 mg/mL or 1.0 mg/mL of Ti particlessignificantly increased sclerostin expression compared with the control group (*p < 0.05)

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