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Journal of Experimental Orthopaedics
Fig. 1 | Journal of Experimental Orthopaedics

Fig. 1

From: Identifying potential patient-specific predictors for anterior cruciate ligament reconstruction outcome – a diagnostic in vitro tissue remodeling platform

Fig. 1

Schematic overview of the experimental procedure in the micro-tissue platform. To the array of micro posts (grey), a suspension of cells and collagen (pink) was added. Cells contracting and applying force to their collagenous environment results in formation of a predominantly isotropic micro-tissue around the constraining posts in the subsequent 48 h. By releasing the tissue constraints of the four outermost posts, a tissue remodeling process is initiated that results in further compaction into a more anisotropic tissue during the next 48 h

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