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Fig. 4 | Journal of Experimental Orthopaedics

Fig. 4

From: Viscosupplementation may preserve tibial cartilage and collagen in osteoarthritis: findings from a preclinical model of osteoarthritis

Fig. 4

ED-1 staining on the lateral tibial surface. a Uninjected left knee. Arrow identifies normal background level of ED-1-positive macrophages in synovium. b PBS injections at Days 7, 14, and 21 in the right knee. Arrow identifies ED-1-positive macrophages surrounding degenerating cartilage fragment in synovium. There is a mild increase over normal background levels, likely as a result of the disease process (rather than the treatments). c IA-BioHA injections (0.5 mg/rat) at Days 7, 14, and 21 in the right knee. Arrow identifies ED-1-positive macrophages in synovium. There is a mild increase over normal background levels, likely as a result of the disease process. Images were acquired at 400x magnification

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