Skip to main content
Journal of Experimental Orthopaedics
Fig. 2 | Journal of Experimental Orthopaedics

Fig. 2

From: Viscosupplementation may preserve tibial cartilage and collagen in osteoarthritis: findings from a preclinical model of osteoarthritis

Fig. 2

Histological scoring for tibial collagen degeneration and amount of normal collagen. Collagen damage is measured with an ocular micrometer as the width of any collagen damage across the tibial plateau. The mean proportion of the tibial surface that showed either normal collagen or total collagen degeneration is shown. Three weekly injections of IA-BioHA showed a significantly greater amount of normal collagen and significantly smaller amount of total collagen degeneration compared to vehicle control. Error bars indicate 1 standard error from the mean. n = 15/group for test article and vehicle control groups, n = 10/group for sham surgery. * different from the D7 and D7, 14, 21 vehicle control groups, p < 0.0001. # different from the respective D7 or D7, 14, 21 vehicle control p = 0.011

Back to article page