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# Table 2 Statistics including correlation with age for 10 analytes

Variable 20’s
N = 13
30’s
N = 13
40’s
N = 13
P by Kruskal-Wallis test P value for pairwise comparison* Spearman’s correlation with age P
20’s vs 30 ‘s 20’s vs 40 ‘s 30’s vs 40 ‘s
PDGF-BB (ng/mL) 3.3 [2.4, 6.5] 3.5 [1.4, 6.2] 2.1 [1.4, 4.9] 0.030 0.72 0.013 0.094 −0.32 0.049
TGF-β1 (ng/mL) 15.4 [11.0, 24.7] 17.1 [11.4, 31.9] 13.1 [11.2, 21.1] 0.12 −0.17 0.295
VEGF (pg/mL) 104 [21, 534] 290 [65, 591] 196 [41, 725] 0.20 0.19 0.325
EGF (pg/mL) 722 [489, 923] 861 [489, 1736] 612 [226, 938] 0.029 0.10 0.18 0.026 −0.19 0.255
FGF (pg/mL) 11 [5, 15] 12 [4, 40] 10 [4, 19] 0.33 −0.20 0.211
HGF (pg/mL) 431 [285, 596] 492 [357, 733] 451 [338, 560] 0.11 0.16 0.341
IGF-1 (ng/mL) 90 [58, 139] 70 [60, 96] 63 [47, 104] 0.027 0.18 0.024 0.10 −0.39 0.014
PLT (×104/μL) 23 [16, 26] 26 [20, 34] 21 [18, 32] 0.004 0.003 0.94 0.024 0.03 0.87
PLT (PRP) (×104/μL) 39 [28, 56] 47 [32, 82] 34 [23, 49] 0.004 0.077 0.16 0.001 −0.23 0.151
1. Values in the table are shown as median [minimum, maximum]
2. PDGF-BB platelet-derived growth factor-BB, TGF-β1 transforming growth factors-β1, VEGF vascular endothelial growth factor, EGF epidermal growth factor, FGF fibroblast growth factor, HGF hepatocyte growth factor, IGF-1 insulin-like growth factor-1
3. *Fisher’s LSD for multiplicity adjustment