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Fig. 2 | Journal of Experimental Orthopaedics

Fig. 2

From: Iodine contrast agents do not influence Platelet-Rich Plasma function at an early time point in vitro

Fig. 2

In Vitro qualitative assessment. a Platelet aggregation depending on the iodine contrast agent. Three groups were compared: control (PRP + phosphate buffer solution), Visipaque270® (PRP + Visipaque270®) and Iopamiron200® (PRP+ Iopamiron200®) (b) Platelet aggregation depending on the iodine concentration of Visipaque®. Two groups were compared: control (PRP + phosphate buffer solution) and Visipaque320®. The percentage of platelet aggregation was assessed by 4 tests: in the presence of adenosine diphosphate (ADP), Collagen, Arachidonic acid (Ar. acid) and thrombin receptor activating peptide (TRAP). c Degranulation: Surface expression of human P-selectin in the presence of PRP + Visipaque270® or PRP + Iopamiron200®, before and after exposure to 25 μM of TRAP. P selectin expression is expressed as the mean fluorescence intensity compare to normal. P-selectin expression ratio corresponds to the ratio between expression after TRAP exposure and before TRAP exposure

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