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Table 1 Experimental conditions used to test the effect of local anaesthetics and Glucosamine on articular cartilage. Radio-labelled sulphur (35-S) uptake was compared to the control solution (M199)

From: Glucosamine reduces the inhibition of proteoglycan metabolism caused by local anaesthetic solution in human articular cartilage: an in vitro study

Experiment Condition Number of specimens Test solution exposure (for 1 h) Recovery Incubation (for 16 h)
1 38 1% Lidocaine (1 ml) M199 (1 ml) + 35-S (5 mCi)
2 38 2% Lidocaine (1 ml) M199 (1 ml) + 35-S (5 mCi)
3 38 0.25% Bupivacaine (1 ml) M199 (1 ml) + 35-S (5 mCi)
4 38 0.5% Bupivacaine (1 ml) M199 (1 ml) + 35-S (5 mCi)
5 38 0.5% Levo-bupivacaine (1 ml) M199 (1 ml) + 35-S (5 mCi)
6 38 Control - M199 (1 ml) M199 (1 ml) + 35-S (5 mCi)
7 26 0.5% Bupivacaine (1 ml) + Glucosamine-6-sulphate (10 mg/100μl) M199 (1 ml) + 35-S (5 mCi)
8 26 0.5% Bupivacaine (1 ml) M199 (1 ml) + Glucosamine-6-sulphate (10 mg/100μl) + 35-S (5 mCi)