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Table 1 Experimental conditions used to test the effect of local anaesthetics and Glucosamine on articular cartilage. Radio-labelled sulphur (35-S) uptake was compared to the control solution (M199)

From: Glucosamine reduces the inhibition of proteoglycan metabolism caused by local anaesthetic solution in human articular cartilage: an in vitro study

Experiment Condition

Number of specimens

Test solution exposure (for 1 h)

Recovery Incubation (for 16 h)

1

38

1% Lidocaine (1 ml)

M199 (1 ml) + 35-S (5 mCi)

2

38

2% Lidocaine (1 ml)

M199 (1 ml) + 35-S (5 mCi)

3

38

0.25% Bupivacaine (1 ml)

M199 (1 ml) + 35-S (5 mCi)

4

38

0.5% Bupivacaine (1 ml)

M199 (1 ml) + 35-S (5 mCi)

5

38

0.5% Levo-bupivacaine (1 ml)

M199 (1 ml) + 35-S (5 mCi)

6

38

Control - M199 (1 ml)

M199 (1 ml) + 35-S (5 mCi)

7

26

0.5% Bupivacaine (1 ml) + Glucosamine-6-sulphate (10 mg/100μl)

M199 (1 ml) + 35-S (5 mCi)

8

26

0.5% Bupivacaine (1 ml)

M199 (1 ml) + Glucosamine-6-sulphate (10 mg/100μl) + 35-S (5 mCi)