Implantation | |||||||
---|---|---|---|---|---|---|---|
Group | Part | Animal no. | Treatment group name | Treatment | Knee | Injection volume gel [μl] | Observation period |
1 | II | 101–103 | Untreated control | - | right | - | 12 weeks |
I | 104–106 | 4 weeks | |||||
2 | II | 107–109 | Gel | 1.75% hyaluronan thiomer gel | right | approx. 60 | 12 weeks |
I | 110–112 | 4 weeks | |||||
3 | II | 113–115 | Gel + matrix | 1.75% hyaluronan thiomer gel + lyophilized 1.5% hyaluronan thiomer matrix | right | approx. 20 | 12 weeks |
I | 116–118 | 4 weeks |