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Table 2 Biomarker Values a

From: Differences in biomarkers of cartilage matrix turnover and their changes over 2 years in adolescent and adult volleyball athletes

  BL Open Adolescents BL Closed Adolescents Adults P-value
CILP-2 [ng/ml] BL 0.56 (−0.059, 1.2) 0.98 (0.60, 1.4) 1.4 (0.90, 2.0) 0.13
FU 2.2 (1.4, 3.1) 3.0 (1.3, 4.6) 2.6 (2.0, 3.2) 0.775
COMP [U/l] BL 15.2 (11.8, 18.5) 11.5 (3.7, 19.3) 12.8 (10.8, 14.8) 0.406
FU 15.0 (13.1, 16.8) 12.1 (6.7, 17.6) 13.4 (11.8, 15.0) 0.537
sC2C [ng/ml] BL 167.9 (108.6, 227.1) 137.5 (18.6, 256.4) 120.5 (90.3, 150.7) 0.177
FU 123.3 (105.8, 140.7) 113.4 (70.2, 156.6) 159.6 (120.0, 199.3) 0.241
CPII [ng/ml] BL 310.4 (212.8, 407.9) 177.2 (−5.1, 359.5) 199.3 (139.7, 258.9) 0.164
FU 176.9 (139.7, 214.1) 161.8 (42.5, 281.0) 262.9 (144.7, 381.0) 0.862
C2C-HUSA [ng/mmol] BL 7.4 (2.3, 12.6) 3.6 (0.21, 7.0) 0.43 (0.33, 0.53) <0.001 * 0.007 **
FU 3.2 (1.9, 4.5) 1.3 (0.53, 2.0) 0.54 (0.39, 0.69) <0.001 * 0.112 **
CTX-II [ng/mmol] BL 10,675.6 (6038.9, 15,312.3) 3710.8 (259.7, 7161.9) 255.4 (177.2, 333.7) <0.001 * 0.030 **
FU 3312.2 (2255.6, 4368.9) 1499.8 (1181.6, 1818.1) 281.1 (203.5, 358.7) <0.001 * 0.034 **
  1. * Statistically significant difference between BL open adolescents and adults
  2. ** Statistically significant difference between BL closed adolescents and adults
  3. a BL baseline, FU follow-up, BL Open Adolescents adolescents with open growth plates at BL, BL Closed Adolescents adolescents with closed growth plates at BL. Data provided as mean (95% confidence interval). P-values refer to differences between the three groups at BL or FU