From: Knee donor-site morbidity after mosaicplasty – a systematic review
First author (year) | Donor site | Plugs size (mm) | No. plugs (range) | Time to surgery (months) | No. of previous surgeries | No. concomitant procedures | Follow-up (months) | Radiological outcomes | Satisfaction (%) | Return to sports activity (%) | Second-look arthroscopy (%) | Complications |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Knee | ||||||||||||
Atik et al. (2005) | Minimal weightbearing area of the patellofemoral joint or the intercondylar notch area | 3.5 | ≤5 | N.R. | N.R. | N.R. | 48 | Normal shiny appearance and color of the grafted area (100 %)a | N.R. | N.R. | 42 | Slight joint effusion (n = 12). |
Espregueira-Mendes et al. (2012) | Upper tibio-fibular joint | N.R. | 2.5 (1-6) | N.R. | N.R. | N.R. | 110.1 | MRI-scoring system: good (26 %), fair (65 %) and poor (10 %)d | 90 | N.R. | N.R. | N.R. |
Gudas et al. (2005) | Lateral/medial margin of the femoral trochlea | 5.5 | 4.3 (3-6) | 21.3 | 0 | N.R. | 37.1 | ICRS: 27 (96 %) good to excellent results.cd | N.R. | 93 | 50 | Superficial infection (n = 2). |
Hangody et al. (2008) | Margin of the medial and lateral femoral condyle superior to the sulcus terminalis and notch area (for larger defects) | N.R. | N.R. | N.R. | N.R. | 783 | At least 12 | N.R. | N.R. | N.R. | 10 | Deep infections (n = 4), painful haemarthroses (n = 56), minor thromboembolic complications (n = 4). |
Hangody et al. (2010) | Margin of the medial and lateral femoral condyle superior to the sulcus terminalis | 4.5-8.5 | 2.7 (1-9) | N.R. | N.R. | 225 | 115.2 | Fairbank: grades I-II in 19 % and grades II-III in 8%c | 90 | 91 | 7 | Septic arthritis (n = 2), intra-articular hemorage (n = 2). |
Jakob et al. (2002) | Medial and the lateral edging of the femoral trochlea and notch area (for larger defects) | 6.3 | 6 (1-16) | N.R. | 3 | 47 | 37 | ICRS: nearly normal (grade II) in 91%d Demarcating border (<1 mm) between the grafted surface and the surrounding cartilaged Smooth or slightly fibrillated surface of autograftsd | 88 | 52 | 24 | Reflex sympathetic dystrophy (n = 1), graft failure (n = 4), severe infection (n = 1) and postoperative joint stiffness (n = 1). |
Kock et al. (2010) | Trochlear border of the lateral femoral condyle | 9.4 | 2.4 (1–4) | N.R. | N.R. | N.R. | 49 | Did not performed radiological evaluation | N.R. | N.R. | N.R. | N.R. |
Koulalis et al. (2004) | Lateral femoral condyle | 2.9 | 2.9 (1–7) | N.R. | N.R. | 3 | 27.2 | ICRS: normal (67 %) and nearly normal (33 %)d Cartilaginous coverage of the defect (100 %)d Osseous integration of the grafts (100 %)d | N.R. | N.R. | 22 | N.R. |
Quarch et al. (2014) | Dorsal medial femoral condyle | 8.5 | 3.8 | N.R. | N.R. | N.R. | 13.8 | Henderson score (modified): 11.1 pointsd | N.R. | N.R. | N.R. | Bone marrow edema with osseous cysts (n = 1). |
Reverte-Vinaixa et al. (2013) | Lateral edge of the trochlea | 9.3 | 2.8 (1-7) | N.R. | 12 | N.R. | 12 | Surface congruency and correct graft integration with no signs of fissuring or delamination (88 %)d | N.R. | N.R. | N.R. | Necrosis and cystic degeneration of the grafts (n = 2) and persistent graft oedema (n = 5). |
Clavé et al. (2016) | Trochlear facets/groove and intercondylar notch | 8.6 | 1.6 (1-4) | 66.1 | 13 | N.R. | 24 | N.R. | N.R. | N.R. | N.R. | Intra-articular effusion (n = 2); hematoma (n = 1); popliteal cyst (n = 1). |
Ankle | ||||||||||||
Ahmad and Jones (2015) | Extra-articular superolateral distal femoral condyle | N.R. | N.R. | N.R. | N.R. | N.R. | 35.2 | Full osteochondral healing (90 %)c | N.R. | N.R. | N.R. | Post-operative superficial wound blistering (n = 1) and non-union graft (n = 2). |
Al-Shaikh et al. (2002) | Trochlear border of the lateral femoral condyle | 8.6 | 1.3 (1-2) | 50.4 | 13 | 1 | 16 | No evidence of graft subsidence and all grafts healed (100 %)c | 83 | N.R. | N.R. | Neuroma (n = 2); superficial wound slough (n = 1); symptomatic hardware (n = 1). |
Baltzer and Arnold (2005) | Superolateral condyle of the ipsilateral knee | N.R. | 1.8 (1-4) | >9 | N.R. | N.R. | Up to 54 | Bone integration into the taluscd | 95 | Most of included participants | At least 58 | N.R. |
Gautier et al. (2002) | Non-weight-bearing trochlear border of the ipsilateral knee | 6.4 | 4.4 (1-6) | N.R. | N.R. | N.R. | 24 | Incorporation of the graft and intergraft intergration (91 %)e | 91 | 100 | 27 | Partial resorption of graft (n = 1) |
Minimal weightbearing areas of the femoral condyles at the level of the patellofemoral joint | 4.5-6.5 (n = 27) 3.5 (n = 9) | 3 (1-6) | 9 | 29 | N.R. | 50.4 | Good incorporation of all the transplanted graftsc | N.R. | N.R. | 22 | None | |
Kim et al. (2012) | Lateral edge of the lateral trochlea | 9.3 | 1.4 (1-2) | 20.4 | 10 | 14 | 34.1 | Congruent graft margins (88 %)a | 95 | N.R. | 100 | Adhesion (n = 15); synovitis (n = 16); incongruent surface of the graft (n = 10); uncovered area (n = 14). |
Lee et al. (2003) | Superomedial margin (nonweightbearing area) of the medial femoral condyle of the ipsilateral knee | 6-7 | 2.2 (2-4) | 12.2 | N.R. | N.R. | 36 | Consistency of articular surface of the grafts and congruity between the native cartilage (88 %)a | N.R. | 76 | 94 | N.R. |
de l'Escalopier et al. (2015) | Medial (n = 15) and lateral (n = 22) edge of the trochlea | 5.7 | 2.3 (1-8) | 29 | 8 | 8 | 76 | Joint space narrowing (16 %) | N.R. | N.R. | N.R. | None |
Reddy et al. (2007) | Intercondylar notch or the lateral femoral condyle proximal to the sulcus terminale | 5.0 | 2.9 (2-4) | N.R. | N.R. | N.R. | 47 | N.R. | 82 | N.R. | N.R. | N.R. |
Valderrabano et al. (2009) | Lateral femoral condyle | N.R. | 3 (2-6) | N.R. | >9 | N.R. | 72 | Partially narrowed cartilage (100 %), no joint space narrowing (67 %) and subchondral bone plate was partially disrupted (58 %) or missing (25 %)bd | 92 | 50 | N.R. | Cyst formation (n = 11); bone bruising (n = 9); loose bodies (n = 5). b |