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Table 2 Population and articular cartilage / osteochondral defects characteristics

From: Knee donor-site morbidity after mosaicplasty – a systematic review

First author (year) Population M : F Age (years) Defect location Defect size mean (range) Defect classification Radiological evaluation
Knee
 Atik et al. (2005) n = 12 6 : 6 38 MFC (n = 9)
LFC (n = 1)
Patella (n = 2)
>1 cm diameter Outerbridge
Grade IV
Arthroscopy
 Espregueira-Mendes et al. (2012) n = 31 22 : 9 30.1 MFC (n = 22)
LFC (n = 7)
Trochlea (n = 1)
Patella (n = 1)
3.3 cm2 ICRS
Grade IV
MRI
 Gudas et al. (2005) n = 28 19 : 10 24.6 MFC (n = 25)
LFC (n = 3)
2.8 cm2 ICRS
OCD (n = 13)
Full-thickness (n = 15)
MRI
Radiography
 Hangody et al. (2008) n = 967 N.R. N.R. Femoral condyle (n = 789)
Patella (n = 147)
Tibia condyles (n = 31)
N.R. Outerbridge
Grade III or IV (66 %)
Osteochondral defects (33 %)
MRI
Radiography
 Hangody et al. (2010) n = 303 N.R. N.R. MFC (n = 187)
LFC (n = 74)
LTC (n = 15)
MTC (n = 1)
Patella (n = 18)
Trochlear (n = 8)
2.8 cm2 (1-5)
1.8 cm2 (1-4)
1.2 cm2 (1-2)
1 cm2
2.4 cm2 (1-3)
2.1 cm2 (1-3.5)
Outerbridge
Grade III or IV (66 %)
Shallow osteochondral lesions (33 %)
MRI
Radiography
 Jakob et al. (2002) n = 42 34 : 18 34 MFC (n = 10)
LFC (n = 5)
Patella (n = 1) b
4.9 cm2
(1.5-16)
ICRS
Grade III (n = 23)
Grade IV (n = 29)
MRI
 Kock et al. (2010) n = 13 8 : 5 33 MFC (n = 10)
LFC (n = 3)
N.R. Full-thickness cartilage lesions Bone scintigraphy
 Koulalis et al. (2004) n = 18 12 : 6 36 MFC (n = 13)
LFC (n = 2)
Patella (n = 3)
Trochlear (n = 1)
2.5 cm2 Outerbridge
Grade IV
MRI
Radiography
 Quarch et al. (2014) n = 16 N.R. 39.7 MFC (n = 12)
LFC (n = 1)
Patella (n = 3)
4.6 cm2 Grade I-IV MRI
 Reverte-Vinaixa et al. (2013) n = 17 12 : 5 35 MFC (n = 3)
LFC (n = 14)
3.4 cm2
(1-4)
Outerbridge
Grade III/IV
MRI
 Clavé et al. (2016) n = 25 20 : 5 28.3 Femoral condyle (n = 25) 3.5 cm2 ICRS
Grade I (n = 1)
Grade III (n = 2)
Grade IV (n = 22)
MRI
Ankle
 Ahmad and Jones (2015) n = 20 11 : 9 41.3 Anteromedial (n = 2) Anterocentral (n = 1)
Anterolateral (n = 3)
Centromedial (n = 7)
Central direct (n = 1)
Centrolateral (n = 2)
Posteromedial (n = 4)
1.6 cm2
(0.7-2.4)
N.R. CT
MRI
Radiography
 Al-Shaikh et al. (2002) n = 19 6 : 13 32 Medial dome (n = 15)
Lateral dome (n = 3)
Both (n = 1)
1.2 cm2
(0.5-4)
Berndt/Hardy classification
Grade I (n = 4)
Grade II (n = 6)
Grade III (n = 2)
Grade IV (n = 7)
MRI
Radiography
 Baltzer and Arnold (2005) n = 43 30 : 13 31.2 Medial (n = 27)
Lateral (n = 14)
Central (n = 2)
1.7 cm2
(up to 3.7 cm2)
Outerbridge
Grade III or IV
MRI
Radiography
 Gautier et al. (2002) n = 11 8 : 3 31.9 Medial (n = 10)
Lateral (n = 1)
1.8 cm2
(0.7-4.2)
Berndt and Harty
Grade II-IV
CT
MRI
Radiography
 Hangody (2001) n = 36 N.R. 27 N.R. 1 cm2 Berndt and Harty classification
Grade III
Grade IV
CT
MRI
Radiography
 Kim et al. (2012) n = 48 34 : 18 48.2 Anteromedial (n = 8) Centrolateral (n = 15) Posteromedial (n = 29) 1.5 cm2
(0.5-2.9)
N.R. MRI
Radiography
 Lee et al. (2003) n = 17 16 : 1 22.7 Medial (n = 16)
Lateral (n = 2)
1.0 cm2
(0.6-4)
Berndt and Harty
Grade III-IV
Arthroscopy
CT
MRI
Radiography
 de l’Escalopier et al. (2015) n = 37 29 : 8 33 Medial (n = 12)
Posteromedial (n = 14)
Lateral (n = 11)
0.85 cm2
(0.4-2.12)
N.R. CT
MRI
Radiography
 Reddy et al. (2007) n = 11 5 : 6 29 Medial (n = 8)
Posteromedial (n = 1)
Central (n = 1)
Anterocentral (n = 1)
1.3 cm2 Full thickness defects MRI
Radiography
 Valderrabano et al. (2009) n = 12a 8 : 4a 43a Medial (n = 7)
Lateral (n = 14)
1.4 cm2
(0.5-3.6)
Berndt/Harty classificationa
Grade IV (n = 9)
Grade V (n = 5)
MRI
SPECT-CT
  1. Legend: MFC Medial femoral condyle, LFC Lateral femoral condyle, LTC Lateral tibial condyle, MTC Medial tibial condyle, N.R. Not reported, ICRS International Cartilage Repair Society score, OCD Osteochondritis dissecans, MRI Magnetic resonance imaging, CT Computed tomography, SPECT-CT Single-photon emission computed tomography
  2. a Report of the 12 included patients on the follow-up, from a cohort of 21 patients; b Results reported from the patients with osteochondritis dissecans and localized degeneration; the other articular cartilage lesions came from other reasons, such as, acute trauma or femoropatellar arthrosis