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Fig. 2 | Journal of Experimental Orthopaedics

Fig. 2

From: Basic science of osteoarthritis

Fig. 2

Factors regulating Wnt signaling in OA osteoblasts (modification from the original drawing representing the canonical Wnt route adapted from Baron & Kneissel 2013). APC, Adenomatous polyposis coli; DKK2, Dickkopf-related protein 2; DVL, Dishevelled protein; FZD, frizzled receptor; GSK3, glycogen synthase kinase 3; HGF, hepatocyte growth factor; LEF, lymphoid enhancing factor; LPR, lipoprotein receptor-related protein; R-Spo2, R-spondin 2; TCF, T-cell factor; TGF-β, transforming growth factor beta

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