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Table 1 Spearman rank order correlations related to the operated limb at experimental end-point between various biologically relevant clinical and end-point measures (p < 0.05), at either 0 or 20 weeks, or the difference in operated limb over time, or between operated and control hind limb

From: Functional outcome measures in a surgical model of hip osteoarthritis in dogs

Clinical factor Clinical or end-point factor ρ
Change in bodyweight 0–20 weeks Operated total joint & femoral head Mankin score −0.82– −0.79
Change in bodyweight 0–20 weeks Range of motion operated limb at 20 weeks 0.89
Range of motion operated limb at 20 weeks Operated total joint and femoral head Mankin score −0.96– −0.93
Range of motion operated limb at 20 weeks Maximum peak pressure, force and impulse O:C at 20 weeks 0.82–0.89
Range of motion operated limb at 20 weeks Impulse O:C 20 weeks 0.82
Difference in range of motion between operated and control 20 weeks Operated acetabulum Mankin score −0.93
Difference in range of motion between operated and control 20 weeks Bodyweight distribution to operated limb at 20 weeks 0.89
Limb circumference operated limb Operated mean synovial score −0.86
Limb circumference operated limb Control mean synovial score 0.79
CBPI 20 weeks Bodyweight distribution change hind limbs 0–20 weeks −0.77
CBPI 20 weeks Bodyweight distribution change forelimbs 0–20 weeks 0.77
CBPI 20 weeks Bodyweight distribution to operated limb at 20 weeks −0.85
Bodyweight distribution to operated limb at 20 weeks Operated acetabulum Mankin score −0.82
Bodyweight distribution change operated 0–20 weeks Operated mean synovial score −0.93
Bodyweight distribution to operated limb at 20 weeks Control limb acetabulum Mankin score zone 2,6 0.79–0.90
Bodyweight distribution to operated limb at 20 weeks Bodyweight distribution to operated limb at 0 weeks 0.86
Bodyweight distribution change operated 0–20 weeks Impulse O:C at 20 weeks 0.79
Maximum force O:C 20 weeks Operated total joint and femoral head Mankin score −0.86– −0.79
Maximum force O:C 20 weeks Control femoral head Mankin score −0.83
Maximum force O:C 20 weeks Impulse O:C 20 weeks 0.96
Maximum peak pressure O:C 20 weeks Operated total joint and femoral head Mankin score −0.96– −0.93
Radiographic score operated 20 weeks Operated mean synovial and total joint Mankin score 0.77–0.79
Compression index operated 20 weeks Operated mean synovial score 0.82
Compression index operated 20 weeks Distraction index operated 20 weeks 0.86
Compression index operated 20 weeks Radiographic score operated 20 weeks 0.77
Compression index operated 20 weeks Mean number night activity bouts 20 weeks −0.79
Distraction index operated 20 weeks Radiographic score operated 0 weeks 0.94
  1. Notes: CBPI canine brief pain inventory, O:C operated vs. control