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Table 3 Level of inflammatory mediators in acute and chronic group

From: Differences in levels of inflammatory mediators in meniscal and synovial tissue of patients with meniscal lesions

  

Meniscus (pg/mg)

Synovium (pg/mg)

  

IM

NIM

p - value

NS

FS

p - value

Mean

Mean

TNF-α

Acute

0.44 ± .14

0.044 ± .007

.043

0.055 ± .004

0.053 ± 0.053

n.s.

Chronic

0.059 ± .042

0.049 ± .022

.03

0.055 ± .006

0.055 ± .006

n.s.

IL-6

Acute

0.12 ± .03

0.055 ± .014

.043

0.087 ± .02

0.051 ± .14

.043

Chronic

0.096 ± .017

0.071 ± .012

.03

0.088 ± .007

0.082 ± .014

.015

NGF

Acute

0.049 ± .082

0.042 ± .084

n.s.

0.053 ± .01

0.061 ± .017

n.s.

Chronic

0.042 ± .004

0.042 ± .005

n.s.

0.057 ± .02

0.061 ± .03

n.s.

  1. TNF-α tumor necrosis factor-alpha, IL-6 interleukin-6, NGF nerve growth factor, IM injured meniscal site, NIM non-injured meniscal site, NS synovium ‘nearest’ the lesion, FS ‘farthest’ synovium, n.s. not significantly different, SD standard deviation