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Table 4 The ICRS II subcategories for the single defect knees and the double defect knees of study 2

From: Experimental articular cartilage repair in the Göttingen minipig: the influence of multiple defects per knee

ICRS II category ADTT proximal ADTT distal ADTT single ABG proximal ABG distal ABG single
Tissue morphology 38.3 ± 8.2 41.7 ± 7.3 36.7 ± 1.7 15.8 ± 6.4 20.0 ± 7.7 11.7 ± 3.3
Material staining 67.3 ± 11.2 70.0 ± 11.3 86.6 ± 8.8 40.0 ± 10 51.7 ± 15.5 35.0 ± 27.8
Cell morphology 40.0 ± 7.2 40.0 ± 8.2 36.7 ± 1.7 16.7 ± 6.3 20.8 ± 7.7 11.7 ± 3.3
Clusters 55.8 ± 14.5 67.6 ± 17.5 90.0 ± 5.7 69.2 ± 12.7 57.5 ± 19 58.3 ± 26.8
Surface architecture 35.0 ± 6.7 38.3 ± 11.1 36.7 ± 18.6 64.2 ± 10.4 40.1 ± 5.5 23.3 ± 13.7
Basal integration 60.0 ± 5.2 52.5 ± 8.7 40.0 ± 0 64.2 ± 5.2 54.2 ± 10.7 25.0 ± 7.6
Tidemark formation 24.2 ± 10.8 20.8 ± 9.3 21.7 ± 8.3 8.3 ± 3.3 19.2 ± 11.6 8.3 ± 4.4
Subchondral bone 23.3 ± 9.4 25.8 ± 9.6 35.0 ± 7.6 45.8 ± 6.9 49.2 ± 10.5 18.3 ± 7.3
Vascularization 58.3 ± 18.5 65.0 ± 14.3 40.0 ± 23.1 35.8 ± 15.1 49.2 ± 21.3 33.3 ± 33
Surface assessment 30.8 ± 7.9 26.7 ± 9.1 31.7 ± 15.9 35.0 ± 11.4 34.2 ± 9.2 21.7 ± 14.8
Deep assessment 47.5 ± 7.3 43.3 ± 7.6 43.3 ± 12 46.7 ± 8.3 58.3 ± 6 18.3 ± 4.4
Overall assessment 48.8 ± 3 50.0 ± 3.3 52.0 ± 3 48.1 ± 3.4 49.4 ± 4.4 31.0 ± 3.7
  1. “Single”, “proximal” and “distal” corresponds to Fig. 2, circle 1, 2 and 3 respectively. No significant difference was found between any defect location in neither the ADTT group nor the ABG group