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Table 4 The ICRS II subcategories for the single defect knees and the double defect knees of study 2

From: Experimental articular cartilage repair in the Göttingen minipig: the influence of multiple defects per knee

ICRS II category

ADTT proximal

ADTT distal

ADTT single

ABG proximal

ABG distal

ABG single

Tissue morphology

38.3 ± 8.2

41.7 ± 7.3

36.7 ± 1.7

15.8 ± 6.4

20.0 ± 7.7

11.7 ± 3.3

Material staining

67.3 ± 11.2

70.0 ± 11.3

86.6 ± 8.8

40.0 ± 10

51.7 ± 15.5

35.0 ± 27.8

Cell morphology

40.0 ± 7.2

40.0 ± 8.2

36.7 ± 1.7

16.7 ± 6.3

20.8 ± 7.7

11.7 ± 3.3

Clusters

55.8 ± 14.5

67.6 ± 17.5

90.0 ± 5.7

69.2 ± 12.7

57.5 ± 19

58.3 ± 26.8

Surface architecture

35.0 ± 6.7

38.3 ± 11.1

36.7 ± 18.6

64.2 ± 10.4

40.1 ± 5.5

23.3 ± 13.7

Basal integration

60.0 ± 5.2

52.5 ± 8.7

40.0 ± 0

64.2 ± 5.2

54.2 ± 10.7

25.0 ± 7.6

Tidemark formation

24.2 ± 10.8

20.8 ± 9.3

21.7 ± 8.3

8.3 ± 3.3

19.2 ± 11.6

8.3 ± 4.4

Subchondral bone

23.3 ± 9.4

25.8 ± 9.6

35.0 ± 7.6

45.8 ± 6.9

49.2 ± 10.5

18.3 ± 7.3

Vascularization

58.3 ± 18.5

65.0 ± 14.3

40.0 ± 23.1

35.8 ± 15.1

49.2 ± 21.3

33.3 ± 33

Surface assessment

30.8 ± 7.9

26.7 ± 9.1

31.7 ± 15.9

35.0 ± 11.4

34.2 ± 9.2

21.7 ± 14.8

Deep assessment

47.5 ± 7.3

43.3 ± 7.6

43.3 ± 12

46.7 ± 8.3

58.3 ± 6

18.3 ± 4.4

Overall assessment

48.8 ± 3

50.0 ± 3.3

52.0 ± 3

48.1 ± 3.4

49.4 ± 4.4

31.0 ± 3.7

  1. “Single”, “proximal” and “distal” corresponds to Fig. 2, circle 1, 2 and 3 respectively. No significant difference was found between any defect location in neither the ADTT group nor the ABG group