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Journal of Experimental Orthopaedics

Table 2 Changes in clinical results before the first HA injection (week 0) and fifth injection (week 5)

From: Changes in synovial fluid biomarkers and clinical efficacy of intra-articular injections of hyaluronic acid for patients with knee osteoarthritis

 

Week 0

Week 5

Pvalue

Range of motion (degrees)

129 ± 13

140 ± 7

<0.001

AKSKS (points)

63.8 ± 10.8

80.0 ± 10.1

<0.001

AKSFS (points)

72.6 ± 11.8

92.7 ± 7.0

<0.001

KOOS Pain (points)

56.2 ± 17.5

81.3 ± 11.2

<0.001

KOOS Symptoms (points)

62.6 ± 14.8

82.4 ± 12.8

<0.001

KOOS Activity of Daily Living (points)

72.6 ± 17.4

90.3 ± 8.1

<0.001

KOOS Sports (points)

45.1 ± 18.6

73.9 ± 13.6

<0.001

KOOS Quality of Life (points)

35.5 ± 14.8

63.6 ± 16.3

<0.001

Total KOOS score

272.0 ± 73.7

391.6 ± 50.8

<0.001

  1. AKSKS: American Knee Society knee score. AKSFS: American Knee Society function score. KOOS: Knee injury and Osteoarthritis Outcome Score.
  2. Data are given as mean ± standard deviation.
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