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Table 1 Mesenchymal stem cells for meniscus regeneration

From: Role of mesenchymal stem cells in meniscal repair

Pro/advantages Cons/disadvantages
• High regenerative potential • High treatment costs
• Self renewal capacity • Regulatory burden
• Cellular modulation at lesion site • Missing knowledge of underlying repair mechanisms
• Potential of differentiation into meniscal repair cells • Possible need for cell expansions prior to application
• Secretion of bioactive substances like growth factors
• Support/promotion of intrinsic meniscal healing capacity