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Journal of Experimental Orthopaedics

Table 2 Rabbit Osteomyelitis (Group 2): comparison of infection detection methods

From: Polymerase Chain Reaction molecular diagnostic technology for monitoring chronic osteomyelitis

   

Microbiological culture and PCR*

   

Metaphysis biopsy

Osteotomy biopsy

   

Needle

Curette

Needle

Curette

Animal no.

Titer (CFU)

Radiograph

Culture

PCR

Culture

PCR

Culture

PCR

Culture

PCR

10

1 × 104

+

-

+

+

-

+

+

+

+

11

1 × 104

+

-

+

+

+

-

+

-

+

12

1 × 104

+

+

+

-

-

+

+

-

-

13

1 × 104

+

-

-

-

+

-

+

-

-

14

1 × 103

-

-

+

-

-

-

+

-

+

15

1 × 102

-

-

+

-

-

-

-

-

+

16

1 × 102

-

-

-

-

+

-

+

-

-

17

1 × 102

-

-

-

+

+

-

-

-

-

18

Sclerosing agent/saline only

-

-

-

-

-

-

-

-

-

  1. *PCR done using Staphylococcus aureus nuc gene primers.
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