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Table 1 Rabbit Osteomyelitis (Group 1): comparison of infection detection methods

From: Polymerase Chain Reaction molecular diagnostic technology for monitoring chronic osteomyelitis

  Infection detection
Animal no. Inoculum (CFU) Microbiological culture Radiography PCR test*
1 1 × 106 + + +
2 1 × 106 + + +
3 1 × 106 + + +
4 1 × 106 + + +
5 1 × 104 + + +
6 1 × 104 - + +
7 1 × 104 + + +**
8 Sclerosing agent and saline only - - -
9 Unoperated control - - -
  1. *PCR done using 16S rRNA gene primers.
  2. **Positive PCR result obtained after two rounds of extraction of sample with Mixed Bed Ion Exchange Resin (see text for details).