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Journal of Experimental Orthopaedics

Table 1 The knee bend test before and after treatment

From: Diminazene aceturate or losartan ameliorates the functional, radiological and histopathological alterations in knee osteoarthritis rodent model: repurposing of the ACE2/Ang1-7/MasR cascade

 

Day 20

Day 41

CN

0.000 ± 0.000

0.375 ± 0.263

OA

1.250* ± 0.250

1.750* ± 0.164

LOS

1.125* ± 0.227

0.625# ± 0.183

DIZE

1.500* ± 0.183

0.500# ± 0.267

  1. Comparisons among groups were analyzed using Kruskal–Wallis Test followed by Dunn's post hoc test. Data are compared at p < 0.05 with CN (*), OA (#). Values are presented as means ± S.E.M (n = 10)
  2. CN control, OA MIA induced osteoarthritis, LOS losartan treated osteoarthritis and DIZE diminazene treated osteoarthritis
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